Evidence map›Paper›PMID 36275073›Full record

ArticleFrontiers in pediatrics2022

High dose of epinephrine does not improve survival of children with out-of-hospital cardiac arrest: Results from the French National Cardiac Arrest Registry.

Morgan Recher, Valentine Canon, Marguerite Lockhart, Martin Lafrance, Hervé Hubert, Stéphane Leteurtre

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Morgan RecherPediatric Intensive Care Unit, CHU Lille, Lille, France.
Valentine CanonULR 2694 - METRICS: Évaluation des technologies de santé et des pratiques médicales, Univ. Lille, CHU Lille, Lille, France.
Marguerite LockhartPediatric Intensive Care Unit, CHU Lille, Lille, France.
Martin LafranceULR 2694 - METRICS: Évaluation des technologies de santé et des pratiques médicales, Univ. Lille, CHU Lille, Lille, France.
Hervé HubertULR 2694 - METRICS: Évaluation des technologies de santé et des pratiques médicales, Univ. Lille, CHU Lille, Lille, France.
Stéphane LeteurtrePediatric Intensive Care Unit, CHU Lille, Lille, France.
Evaluation des technologies de santé et des pratiques médicalesCentre Hospitalier Universitaire de Lille · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The pediatric resuscitation guidelines recommend the use of 0. 01 mg kg Methods: This was a multicenter comparative Results: The analysis included 755 patients; 400 (53%) received a high dose and 355 (47%) received a standard dose of epinephrine. The median dose (mg kg Conclusion: More than 50% of the patients did not receive the recommended epinephrine dose during resuscitation. There was no association between patients receiving a high dose or standard dose of epinephrine with the 30-day survival or survival status at hospital discharge. Collaboration across multiple cardiac arrest registries is needed to study the application of pediatric guidelines.

Indexed as

cardiopulmonary resuscitationchildrenepinephrineguidelinesout-of-hospital cardiac arrest

Identifiers

PMID36275073
PMCPMC9583001
OpenAlexW4303184723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.