SynthesisFrontiers in pediatrics2022
Association between maternal lipid levels during pregnancy and delivery of small for gestational age: A systematic review and meta-analysis.
Synthesis in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Gardnerella enrichment in the vaginal microbiome of women with gestational diabetes mellitus is associated with lower fetal birthweight percentiles.Diabetologia · 2026Observational
- Relationship between maternal lipid profile during the third trimester and the risk of small-for-gestational-age birth: exploring inadequate gestational weight gain as a mediator.Lipids in health and disease · 2026Article
- Prevalence and factors associated with preterm small-for-gestational-age neonates: a multi-center survey in China.BMC pediatrics · 2026Article
- The metabolic implications of maternal exercise: effects on pregnant women and their offspring.Frontiers in nutrition · 2026Review
- Lipidomic signatures in maternal blood and placenta: Systematic evidence linking lipid profiles to pregnancy outcomes and fetal growth.Metabolism open · 2025Review
- Gestational Diabetes Mellitus: The Dual Risk of Small and Large for Gestational Age: A Narrative Review.Medical sciences (Basel, Switzerland) · 2025Review
- Characteristics, Physiopathology and Management of Dyslipidemias in Pregnancy: A Narrative Review.Nutrients · 2024Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Studies investigating the relationship between gestational dyslipidemia and small for gestational age (SGA) have reported differing results. This review was performed to determine whether maternal lipid levels during pregnancy were associated with SGA. Methods: Literature searches for relevant studies were conducted systematically from establishment until February 2022 with PubMed, Embase, Cochrane Library and Web of Science. Risk of bias was assessed with the Newcastle-Ottawa Scale and 11-item checklist. According to the classification of GHD parameters, meta-analyses reporting cases regarding total cholesterol (TC), triglycerides (TG), low-density lipoprotein-cholesterol (LDL-C) and high-density lipoprotein-cholesterol (HDL-C) were performed respectively. If I Results: Eight studies (14,213 pregnancies) were included. Decreased levels of TC (MD -0.13; 95% CI -0.24 to -0.02), TG (MD -0.09; 95% CI -0.14 to -0.03) and LDL-C (MD -0.12; 95% CI -0.23 to -0.00) were risk factors for SGA infant birth. No evident association was observed between HDL-C and delivery of SGA (MD -0.08; 95% CI -0.19 to 0.02). Conclusion: Gestations complicated with dyslipidemia, especially lower concentrations of TC, TG and LDL-C, were at significantly higher risk of delivery of SGA. Systematic review registration: [www.crd.york.ac.uk/prospero], identifier [CRD42022304648].
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