Evidence map›Paper›PMID 36275049›Full record

ArticleFrontiers in pediatrics2022

Effect of nationwide reimbursement of real-time continuous glucose monitoring on HbA1c, hypoglycemia and quality of life in a pediatric type 1 diabetes population: The RESCUE-pediatrics study.

Francesca De Ridder, Sara Charleer, Seppe Jacobs, Nancy Bolsens, Kristien J Ledeganck, Sara Van Aken, Jesse Vanbesien, Inge Gies, Kristina Casteels, Guy Massa and 7 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02601729 (Clinical Impact of RT-CGM Reimbursement in Belgium), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02601729 completednot on this map

Clinical Impact of RT-CGM Reimbursement in Belgium: a Multicenter Real-life Observational Study

TypeobservationalSponsorKU LeuvenRan2014 to 2019Enrolled589ConditionsDiabetes, Type 1
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Article
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  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 1 country.

Francesca De RidderLaboratory of Experimental Medicine and Pediatrics (LEMP) and Member of the Infla-Med Center of Excellence, Faculty of Medicine and Health Science, University of Antwerp, Antwerp, Belgium.
Sara CharleerDepartment of Endocrinology, University Hospitals Leuven, Catholic University of Leuven (KU Leuven), Leuven, Belgium.
Seppe JacobsDepartment of Endocrinology-Diabetology-Metabolism, Antwerp University Hospital (UZA), Antwerp, Belgium.
Nancy BolsensDepartment of Endocrinology-Diabetology-Metabolism, Antwerp University Hospital (UZA), Antwerp, Belgium.
Kristien J LedeganckLaboratory of Experimental Medicine and Pediatrics (LEMP) and Member of the Infla-Med Center of Excellence, Faculty of Medicine and Health Science, University of Antwerp, Antwerp, Belgium.
Sara Van AkenDepartment of Pediatrics, University Hospital Ghent, Ghent, Belgium.
Jesse VanbesienDepartment of Pediatrics, University Hospital Brussels, Free University of Brussels (VUB), Brussels, Belgium.
Inge GiesDepartment of Pediatrics, University Hospital Brussels, Free University of Brussels (VUB), Brussels, Belgium.
Kristina CasteelsDepartment of Pediatrics, University Hospitals Leuven, Leuven, Belgium.
Guy MassaDepartment of Pediatrics, Jessa Hospital, Hasselt, Belgium.
Philippe A LysyDepartment of Pediatrics, University Hospital Saint-Luc, Brussels, Belgium.
Karl LoggheDepartment of Pediatrics, General Hospital Delta, Roeselare, Belgium.
Marie-Christine LebrethonDepartment of Pediatrics, University Hospital of Liège, Liège, Belgium.
Sylvia DepoorterDepartment of Pediatrics, General Hospital Sint-Jan Bruges, Bruges, Belgium.
Pieter GillardFund for Scientific Research (FWO), Brussels, Belgium.
Christophe De BlockLaboratory of Experimental Medicine and Pediatrics (LEMP) and Member of the Infla-Med Center of Excellence, Faculty of Medicine and Health Science, University of Antwerp, Antwerp, Belgium.
Marieke den BrinkerLaboratory of Experimental Medicine and Pediatrics (LEMP) and Member of the Infla-Med Center of Excellence, Faculty of Medicine and Health Science, University of Antwerp, Antwerp, Belgium.
Antwerp University Hospital · BEKU Leuven · BEUniversity of Antwerp · BEAZ Delta · BEAZ Sint-Jan · BECliniques Universitaires Saint-Luc · BEGhent University Hospital · BEJessa Hospital · BEUniversity of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Real-time continuous glucose monitoring (RT-CGM) can improve metabolic control and quality of life (QoL), but long-term real-world data in children with type 1 diabetes (T1D) are scarce. Over a period of 24 months, we assessed the impact of RT-CGM reimbursement on glycemic control and QoL in children/adolescents with T1D treated with insulin pumps. Research design and methods: We conducted a multicenter prospective observational study. Primary endpoint was the change in HbA1c. Secondary endpoints included change in time in hypoglycemia, QoL, hospitalizations for hypoglycemia and/or ketoacidosis and absenteeism (school for children, work for parents). Results: Between December 2014 and February 2019, 75 children/adolescents were followed for 12 ( Conclusion: RT-CGM in pump-treated children/adolescents with T1D showed a temporary improvement in HbA1c in participants with a baseline HbA1c ≥ 7.5%, without increasing time in hypoglycemia. QoL was not affected. Importantly, RT-CGM reduced the need for assistance by ambulance due to hypoglycemia and reduced work absenteeism for parents after 24 months. Clinical trial registration: [ClinicalTrials.gov], identifier [NCT02601729].

Indexed as

HbA1chypoglycemiaquality of lifereal-time continuous glucose monitoring (RT-CGM)time in rangetype 1 diabetes

Identifiers

PMID36275049
PMCPMC9582657
OpenAlexW4302286625

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.