Evidence map›Paper›PMID 36275026›Full record

ArticleFrontiers in cellular and infection microbiology2022

The oral-gut axis: Salivary and fecal microbiome dysbiosis in patients with inflammatory bowel disease.

Mohamed M H Abdelbary, Maximilian Hatting, Alexandra Bott, Andrea Dahlhausen, Doris Keller, Christian Trautwein, Georg Conrads

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Meta-Analysis of the Gut Microbiome: An African American Representation.International journal of environmental research and public health · 2025
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Microorganisms · 2026
    Review
  6. Article
  7. [The Role of Salivary Microbiota in Oral and Systemic Disease Development and Diagnosis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. [The Impact of Oral Microecology on the Development of Inflammatory Bowel Disease].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mohamed M H AbdelbaryDivision of Oral Microbiology and Immunology, Department of Operative Dentistry, Periodontology and Preventive Dentistry, Rheinisch-Westfälische Technische Hochschule (RWTH) University Hospital, Aachen, Germany.
Maximilian HattingDepartment of Medicine III, RWTH University Hospital, Aachen, Germany.
Alexandra BottDivision of Oral Microbiology and Immunology, Department of Operative Dentistry, Periodontology and Preventive Dentistry, Rheinisch-Westfälische Technische Hochschule (RWTH) University Hospital, Aachen, Germany.
Andrea DahlhausenUniversity Medical Center for Occupational Medicine, RWTH University, Aachen, Germany.
Doris KellerUniversity Medical Center for Occupational Medicine, RWTH University, Aachen, Germany.
Christian TrautweinDepartment of Medicine III, RWTH University Hospital, Aachen, Germany.
Georg ConradsDivision of Oral Microbiology and Immunology, Department of Operative Dentistry, Periodontology and Preventive Dentistry, Rheinisch-Westfälische Technische Hochschule (RWTH) University Hospital, Aachen, Germany.
Westfälische Hochschule · DERWTH Aachen University · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders that fall into two main categories: Crohn's disease (CD) and ulcerative colitis (UC). The gastrointestinal tract extends from the mouth to the anus and harbors diverse bacterial communities. Several sequencing-based studies have identified an intestinal enrichment of oral-associated bacteria and demonstrated their ability to induce intestinal inflammation in mice, suggesting that intestinal pathobionts originate from the oral cavity, particularly members of the genus

Indexed as

Gastrointestinal MicrobiomeInflammatory Bowel DiseasesMicrobiotaAnimalsBacteriaCytokinesDysbiosisEscherichiaFecesInflammationMicePhylogenyRNA, Ribosomal, 16SCytokinesRNA, Ribosomal, 16Sfecal microbiomeinflammatory bowel diseaseoral-gut axisPrevotella spp.salivary microbiomeStreptococcus spp.Veillonella spp.

Identifiers

PMID36275026
PMCPMC9585322
OpenAlexW4303183348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.