Evidence map›Paper›PMID 36274962›Full record

ArticleAJOG global reports2022

Low-fat dietary pattern reduces urinary incontinence in postmenopausal women: post hoc analysis of the Women's Health Initiative Diet Modification Trial.

Lisa J Rogo-Gupta, Lingyao Yang, Marcia L Stefanick, Haley Hedlin, Robert Wallace, Nancy Woods, Benjamin N Breyer, Mathew D Sorensen, Bertha Chen

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In one paragraph

Article in AJOG global reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Lisa J Rogo-GuptaDivision of Urogynecology and Pelvic Reconstructive Surgery, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA (Drs Rogo-Gupta and Chen).
Lingyao YangQuantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA (Ms Yang and Dr Hedlin).
Marcia L StefanickDepartment of Medicine, Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA (Dr Stefanick).
Haley HedlinQuantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA (Ms Yang and Dr Hedlin).
Robert WallaceDepartment of Epidemiology, University of Iowa College of Public Health, Iowa City, IA (Dr Wallace).
Nancy WoodsSchool of Nursing, University of Washington, Seattle, WA (Dr Woods).
Benjamin N BreyerDepartments of Urology and Epidemiology and Biostatics, University of California San Francisco, San Francisco, CA (Dr Breyer).
Mathew D SorensenDepartment of Urology, University of Washington School of Medicine, Seattle, WA (Dr Sorensen).
Bertha ChenDivision of Urogynecology and Pelvic Reconstructive Surgery, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA (Drs Rogo-Gupta and Chen).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrinary incontinence affects >40% of women in the United States, with an annual societal cost of >$12 billion and demonstrated associations with depressive symptoms, social isolation, and loss of work productivity. Weight has been established as an exposure that increases urinary incontinence risk and certain dietary components have been associated with urinary incontinence symptoms. We hypothesized that diet plays a key role in the association between weight and urinary incontinence in US women.

objectiveThis study aimed to examine the effect of a low-fat diet on urinary incontinence in postmenopausal women as a post hoc analysis of a randomized controlled trial of diet modification. STUDY

designThis was a post hoc analysis of the Women's Health Initiative Dietary Modification randomized controlled trial of 48,835 postmenopausal women from 40 US centers assigned to a dietary intervention (20% energy from fat, 5 fruits or vegetable servings, and 6 whole grain servings daily and an intensive behavioral modification program) or to the usual diet comparison group. The outcome was urinary incontinence at 1 year.

resultsOf the participants, 60% were randomized to the usual diet comparison group and 40% to the dietary modification intervention. After adjusting for weight change, women assigned to the dietary modification intervention were less likely to report urinary incontinence (odds ratio, 0.94; 95% confidence interval, 0.90-0.98;

conclusionDietary modification may be a reasonable treatment for postmenopausal women with incontinence and also a urinary incontinence prevention strategy for continent women. Our results provide evidence to support a randomized clinical trial to determine whether a reduced fat-intake dietary modification is an effective intervention for the prevention and treatment of urinary incontinence. In addition to providing further insights into mechanisms of lower urinary tract symptoms, these findings may have a substantial impact on public health based on the evidence that diet seems to be a modifiable risk factor for urinary incontinence.

Indexed as

dietmenopausepostmenopauseurinary incontinenceweightWomen's Health InitiativeWomen's Health Initiative dietary modification

Identifiers

PMID36274962
PMCPMC9563654

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.