Evidence map›Paper›PMID 36274876›Full record

ArticleJournal of maxillofacial and oral surgery2022

Analgesia and Side Effects of Codeine Phosphate Associated with Paracetamol Versus Oxycodone After the Extraction of Mandibular Third Molars: A Randomized Double-Blind Clinical Trial Using the Split-Mouth Model.

Matheus Furtado de Carvalho, Gabriela de Matos Silveira, Paula Afonso Rodrigues de Carvalho, Isabel Cristina Gonçalves Leite, Maria da Graça Naclério-Homem

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of maxillofacial and oral surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Matheus Furtado de CarvalhoFaculty of Dentistry, Department of Oral and Maxillofacial Surgery, Federal University of Juiz de Fora, Rua José Lourenço Kelmer, s/n, São Pedro, Juiz de Fora, MG CEP: 36036-900 Brazil.ORCID https://orcid.org/0000-0002-4485-9314
Gabriela de Matos SilveiraFaculty of Dentistry, Department of Oral and Maxillofacial Surgery, Federal University of Juiz de Fora, Rua José Lourenço Kelmer, s/n, São Pedro, Juiz de Fora, MG CEP: 36036-900 Brazil.ORCID https://orcid.org/0000-0003-1560-1493
Paula Afonso Rodrigues de CarvalhoFaculty of Medicine, Department of Public Health, Federal University of Juiz de Fora, Rua José Lourenço Kelmer, s/n, São Pedro, Juiz de Fora, MG CEP: 36036-900 Brazil.ORCID https://orcid.org/0000-0002-9009-9221
Isabel Cristina Gonçalves LeiteFaculty of Medicine, Department of Public Health, Federal University of Juiz de Fora, Rua José Lourenço Kelmer, s/n, São Pedro, Juiz de Fora, MG CEP: 36036-900 Brazil.ORCID https://orcid.org/0000-0003-1258-7331
Maria da Graça Naclério-HomemFaculty of Dentistry, Department of Oral and Maxillofacial Surgery, Traumatology and Prosthesis, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-1329-1698
Universidade Federal de Juiz de Fora · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To assess the analgesia and side effects of 10 mg oxycodone as compared to 30 mg of codeine phosphate associated with 500 mg of paracetamol after bilateral lower third molar extraction. Methods: This is a prospective, randomized, double-blind study applied to a sample of 16 patients. They were evaluated for seven days postoperatively, and the mean score of the visual analogue scale (VAS) of pain between test and control medications was assessed by the Wilcoxon distribution. The side effects of these medications were assessed by the Q Cochran test. A Results: The mean score of the VAS of pain was higher in the oxycodone side, where few patients reported the use of rescue analgesic. There was no report of rescue medication in codeine phosphate associated with paracetamol side. The most common side effects reported in both groups, predominantly in patients using the oxycodone, were drowsiness, dizziness, and headache. Conclusion: The use of codeine phosphate associated with paracetamol after the extraction of impacted mandibular third molars is a better choice than oxycodone for controlling postoperative pain. Trial Registration Number and Date of Registration: RBR-8ntwmyq 07/07/2021.

Indexed as

Codeine phosphateMolar, thirdOxycodonePain, postoperativeTooth extraction

Identifiers

PMID36274876
PMCPMC9474989
OpenAlexW4293185521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.