Evidence map›Paper›PMID 36274738›Full record

ArticleFrontiers in microbiology2022

Artificial rearing alters intestinal microbiota and induces inflammatory response in piglets.

Qi Han, Xiaohong Zhang, Haoyang Nian, Honggui Liu, Xiang Li, Runxiang Zhang, Jun Bao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Porcine intestinal goblet cells: Guardians of mucosal immunity and barrier function.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qi HanCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Xiaohong ZhangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Haoyang NianCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Honggui LiuCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Xiang LiCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Runxiang ZhangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Jun BaoCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Northeast Agricultural University · CNMinistry of Agriculture and Rural Affairs · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the ongoing genetic selection for high prolificacy in sow lines and the improvements in environment and farm management, litter size has increased in recent years. Artificial rearing is becoming widely used to raise the surplus piglets in pig industry. This study aimed to investigate the changes that happened in the morphology, microbiota, mucosal barrier function, and transcriptome caused by artificial rearing in piglet colon. Two hundred and forty newborn piglets were randomly assigned into three treatments, sow rearing until weaning (CON group), artificial rearing from day 21 (AR21 group), and artificial rearing from day 7 (AR7 group). On day 35, the piglets were euthanized to collect colon samples. The results showed that the artificially reared-piglets displayed increased pre-weaning diarrhea incidence and reduced growth performance. Artificial rearing changed the diversity and structure of colonic microbiota and increased relative abundance of harmful bacteria, such as

Indexed as

artificial rearingdiarrheamicrobiotaNF-κB pathwaypiglet

Identifiers

PMID36274738
PMCPMC9584613
OpenAlexW4302305172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.