Evidence map›Paper›PMID 36274100›Full record

ArticlePflugers Archiv : European journal of physiology2023

Inhibition of late sodium current via PI3K/Akt signaling prevents cellular remodeling in tachypacing-induced HL-1 atrial myocytes.

Tae Hee Ko, Daun Jeong, Byeongil Yu, Ji Eun Song, Qui Anh Le, Sun-Hee Woo, Jong-Il Choi

Open access · hybridAbstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Cardiovascular Toxicity of BTKi in Chronic B-Cell Malignancies.Reviews in cardiovascular medicine · 2026
    Review
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Tae Hee Ko *Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Medical Centre, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Daun Jeong *Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Medical Centre, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Byeongil YuDivision of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Medical Centre, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Ji Eun SongDivision of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Medical Centre, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Qui Anh LeLaboratory of Pathophysiology, College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 34134, Republic of Korea.
Sun-Hee WooLaboratory of Pathophysiology, College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 34134, Republic of Korea.
Jong-Il ChoiDivision of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Medical Centre, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea. jongilchoi@korea.ac.kr.ORCID 0000-0001-6617-508X
Korea University · KRChungnam National University · KRKorea Development Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An aberrant late sodium current (I

Indexed as

Atrial FibrillationAtrial RemodelingAction PotentialsHeart AtriaHumansMyocytes, CardiacPhosphatidylinositol 3-KinasePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSodiumPhosphatidylinositol 3-KinasePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSodiumAtrial FibrillationElectrical remodelingLate sodium currentPI3K/Akt signalingTachypacing

Identifiers

PMID36274100
PMCPMC9849166
OpenAlexW4307180329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.