Evidence map›Paper›PMID 36274078›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Current quality of life assessment tools may not fully address dermatological adverse events from anti-cancer therapies.

Tara Behroozian, Sakeena Fatima, Samuel Finkelstein, Lauren Kanee, Pierluigi Bonomo, Julie Ryan Wolf, Vassilios Vassiliou, Corina van den Hurk, Edward Chow, Mara Beveridge

Abstract readReview
PubMed Publisher
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Barrier Films and Dressings for the Prevention of Acute Radiation Dermatitis: A Systematic Review and Meta-Analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  2. Natural and miscellaneous agents for the prevention of acute radiation dermatitis: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  3. Perspectives on managing skin manifestations in cancer patients: a multidisciplinary mixed-method survey of oncologists and dermatologists.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Navigating trial design in radiation dermatitis research: paths to improvement.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  5. Observational
  6. Article
  7. The role of dermocosmetics in the management of cancer-related skin toxicities: international expert consensus.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 6 countries.

Tara BehroozianMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada. tara.behroozian@medportal.ca.
Sakeena FatimaDepartment of Dermatology, University Hospitals, Cleveland, OH, USA.
Samuel FinkelsteinFaculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lauren KaneeFaculty of Medicine, University of Toronto, Toronto, ON, Canada.
Pierluigi BonomoDepartment of Radiation Oncology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Julie Ryan WolfDepartment of Dermatology, University of Rochester Medical Centre, Rochester, NY, USA.
Vassilios VassiliouDepartment of Radiation Oncology, Bank of Cyprus Oncology Centre, Nicosia, Cyprus.
Corina van den HurkNetherlands Comprehensive Cancer Organization, Utrecht, Netherlands.
Edward ChowDepartment of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
Mara BeveridgeDepartment of Dermatology, University Hospitals, Cleveland, OH, USA.
University Hospitals of Cleveland · USUniversity of Toronto · CAAzienda Ospedaliero-Universitaria Careggi · ITBank of Cyprus Oncology Center · CYMcMaster University · CANetherlands Comprehensive Cancer Organisation · NLTel Aviv University · ILUniversity of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Supportive oncodermatology is a burgeoning new field within dermatology tasked with caring for the unique dermatologic needs of patients with cancer. Patients with dermatologic adverse events (dAEs) from localized and systemic anti-cancer therapies commonly experience significant distress and reduced health-related quality of life (HRQoL). Emerging dAEs is often overlooked by clinicians and researchers, despite their considerable impacts on treatment completion and patient self-esteem. Specific HRQoL issues experienced by cancer patients with dAEs include psychosocial distress and treatment interruption or cessation. Existing HRQoL assessment indices unfortunately fall short when assessing HRQoL in patients with dAEs from anti-cancer therapies due to the lack of specificity to patients' symptoms and inability to fully encompass the unique needs of this population. Additionally, the variability in HRQoL assessments across studies is substantial, suggesting the need for a standardized HRQoL measure. Here, we review the burden of dAEs and the existing validated tools used to measure them, while outlining strategies for modification to achieve optimal HRQoL assessment in patients with dAEs from anti-cancer therapies and address the HRQoL gap in supportive oncodermatology. Amongst the current tools, Skindex-16 most closely addresses the required skin-specific HRQoL metrics, but still lacks a few key cancer-specific measures. Other general HRQoL tools are well-tailored to cancer patients, but lack skin-specific questions.

Indexed as

NeoplasmsQuality of LifeHumansAnti-cancer therapyCancerDermatologic adverse eventOncodermatologyQuality of life

Identifiers

PMID36274078
OpenAlexW4307180561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.