Evidence map›Paper›PMID 36273917›Full record

ArticleJournal of atherosclerosis and thrombosis2023

Angiographic Coronary Calcification: A Simple Predictor of Long-Term Clinical Outcomes in Patients with Acute Myocardial Infarction.

Shun Ishibashi, Kenichi Sakakura, Satoshi Asada, Yousuke Taniguchi, Hiroyuki Jinnouchi, Takunori Tsukui, Yusuke Watanabe, Kei Yamamoto, Masaru Seguchi, Hiroshi Wada and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Sex-Related Differences in the Prevalence and Clinical Outcomes of Moderate-to-Severe Coronary Artery Calcification in Patients Undergoing Percutaneous Coronary Intervention.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Shun IshibashiDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Kenichi SakakuraDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Satoshi AsadaDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Yousuke TaniguchiDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Hiroyuki JinnouchiDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Takunori TsukuiDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Yusuke WatanabeDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Kei YamamotoDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Masaru SeguchiDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Hiroshi WadaDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Hideo FujitaDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University.
Jichi Medical University · JPJichi Medical University Saitama Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsCoronary calcification detected by coronary angiography is a simple risk marker for long-term clinical outcomes in stable coronary artery disease. However, the significance of angiographic coronary calcification in the culprit lesion of acute myocardial infarction (AMI) has not been fully discussed. The purpose of this retrospective study was to assess the usefulness of angiographic coronary calcification as a risk marker for long-term clinical outcomes following percutaneous coronary intervention to the culprit lesions of AMI.

methodsWe included 1209 patients with AMI and divided them into the none-mild calcification group (n=923) and the moderate-severe calcification group (n=286) according to angiographic coronary calcification in the culprit lesion of AMI. The primary endpoint was the occurrence of major adverse cardiac events (MACE), which was defined as a composite of all-cause death, nonfatal MI, readmission for heart failure, and ischemia-driven target vessel revascularization.

resultsThe median follow-up duration was 542 (Q1: 182, Q3: 990) days. A total of 345 MACE were observed during the study period. The occurrence of MACE was significantly greater in the moderate-severe calcification group than in the none-mild calcification group (43.4% vs. 23.9%, p<0.001). In the multivariate Cox hazard model, moderate-severe calcification was significantly associated with MACE (hazard ratio 1.302, 95% confidence interval 1.011-1.677, p=0.041) after controlling multiple confounding factors.

conclusionsAngiographically moderate to severe calcification in AMI culprit lesion was associated with long-term worse clinical outcomes. Angiographic coronary calcification can be a simple risk marker in patients after AMI.

Indexed as

CalcinosisCoronary Artery DiseaseMyocardial InfarctionCoronary AngiographyHumansPercutaneous Coronary InterventionRetrospective StudiesRisk FactorsTreatment OutcomeAcute myocardial infarctionAngiographic coronary calcificationMajor adverse cardiac eventsPercutaneous coronary intervention

Identifiers

PMID36273917
PMCPMC10406646
OpenAlexW4307178532

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.