Evidence map›Paper›PMID 36273237›Full record

ArticleScientific reports2022

RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer.

Akira Nakazato, Mai Mochizuki, Rie Shibuya-Takahashi, Haruna Fujimori, Keitaro Fujii, Satoshi Saijoh, Shinkichi Morita, Tomoko Yamazaki, Takayuki Imai, Ikuro Sato and 8 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. ERCC1/NGFR affects prognosis in basal-like breast cancer.European journal of medical research · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Akira NakazatoDivision of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Mai MochizukiDivision of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Rie Shibuya-TakahashiDivision of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Haruna FujimoriDivision of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Keitaro FujiiDepartment of Head and Neck Surgery, Miyagi Cancer Center, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Satoshi SaijohDepartment of Head and Neck Surgery, Miyagi Cancer Center, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Shinkichi MoritaDepartment of Head and Neck Surgery, Miyagi Cancer Center, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Tomoko YamazakiDepartment of Head and Neck Medical Oncology, Miyagi Cancer Center, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Takayuki ImaiDepartment of Head and Neck Surgery, Miyagi Cancer Center, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Ikuro SatoDepartment of Pathology, Miyagi Cancer Center, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Kennichi SatohDivision of Gastroenterology, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyaginoku, Sendai, Miyagi, 983-8536, Japan.
Kazunori YamaguchiDivision of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Kazuo SugamuraDivision of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Jun YasudaDivision of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Kazuto MatsuuraDepartment of Head and Neck Surgery, National Cancer Center Hospital East, Kashiwanoha, Kashiwa, Chiba, Japan.
Hideo ShojakuDepartment of Otolaryngology, University of Toyama, Sugitani, Toyama, Japan.
Yukinori AsadaDepartment of Head and Neck Surgery, Miyagi Cancer Center, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan.
Keiichi TamaiDivision of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiote, Natori, Miyagi, Japan. tamaikeiichi@med.tohoku.ac.jp.
Miyagi Prefectural Hospital Organization · JPUniversity of Toyama · JPNational Cancer Center Hospital East · JPTohoku Medical and Pharmaceutical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD271 (also referred to as nerve growth factor receptor or p75

Indexed as

Hypopharyngeal NeoplasmsAdapaleneCell ProliferationHumansNerve Tissue ProteinsNF-kappa BReceptors, Nerve Growth FactorTranscription Factor RelAAdapaleneNerve Tissue ProteinsNF-kappa BNGFR protein, humanReceptors, Nerve Growth FactorRELA protein, humanTranscription Factor RelA

Identifiers

PMID36273237
PMCPMC9588052
OpenAlexW4307139483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.