ArticleGenetics, selection, evolution : GSE2022
Genetic parameters of colostrum and calf serum antibodies in Swedish dairy cattle.
Article in Genetics, selection, evolution : GSE, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Genome-wide association study reveals key genomic regions underlying colostrability in Italian Holstein cattle.Genetics, selection, evolution : GSE · 2026Article
- Evaluation of factors associated with immunoglobulin, protein, fat and lactose concentrations in colostrum of dairy cows from Austria.Acta veterinaria Scandinavica · 2024Article
- Holstein × Montbéliarde-sired F1 generation crossbred female calves have an increased cellular immune response potential compared with purebred Holsteins.The veterinary quarterly · 2024Article
- Review
- Assessment of Herd, Calf, and Colostrum Management Practices on Austrian Dairy Farms Using a Scoring System.Animals : an open access journal from MDPI · 2023Article
- Factors Associated with Colostrum Quality, the Failure of Transfer of Passive Immunity, and the Impact on Calf Health in the First Three Weeks of Life.Animals : an open access journal from MDPI · 2023Article
- Genetic Parameters of Serum Total Protein Concentration Measured with a Brix Refractometer in Holstein Newborn Calves and Fresh Cows.Animals : an open access journal from MDPI · 2023Article
- Genetic characteristics of colostrum refractive index and its use as a proxy for the concentration of immunoglobulins in Holstein cattle.Genetics, selection, evolution : GSE · 2022Article
- Concentration and heritability of immunoglobulin G and natural antibody immunoglobulin M in dairy and beef colostrum along with serum total protein in their calves.Journal of animal science · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundA sufficient IgG content in the colostrum is essential for the newborn calf, as it provides passive immunity which substantially affects the probability of survival during rearing. Failure of passive transfer (FPT) occurs when a calf does not absorb enough antibodies from the colostrum and is defined by an IgG concentration in calf serum lower than 10 g/L. Apart from delayed access to colostrum, FPT can be due to a low production of IgG in the mother or poor IgG absorption by the calf. The aim of this study was to estimate the genetic background of antibody levels and indicator traits for antibodies in the colostrum and calf serum, and their correlation with milk production.
resultsColostrum data were available for 1340 dairy cows with at least one calving and calf serum data were available for 886 calves from these cows. Indicator traits for antibody concentrations were estimated using refractometry (a digital Brix refractometer for colostrum and an optical refractometer for serum), and enzyme-linked immunosorbent assays (ELISA) were used to determine the levels of total IgG and natural antibodies (NAb) of various antibody isotypes in the colostrum and calf serum. Colostrum traits had heritabilities ranging from 0.16 to 0.31 with repeatabilities ranging from 0.21 to 0.55. Brix percentages had positive genetic correlations with all colostrum antibody traits including total IgG (0.68). Calf serum antibody concentrations had heritabilities ranging from 0.25 to 0.59, with a significant maternal effect accounting for 17 to 27% of the variance. When later in life calves produced their first lactation, the lactation average somatic cell score was found to be negatively correlated with NAb levels in calf serum.
conclusionsOur results suggest that antibody levels in the colostrum and calf serum can be increased by means of selection.
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