Evidence map›Paper›PMID 36273105›Full record

ArticleLeukemia2022

Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.

Sonja I Berndt, Joseph Vijai, Yolanda Benavente, Nicola J Camp, Alexandra Nieters, Zhaoming Wang, Karin E Smedby, Geffen Kleinstern, Henrik Hjalgrim, Caroline Besson and 130 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Leukemia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Replication of a GWAS signal nearBlood neoplasia · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

140 authors at 20 institutions in 15 countries.

Sonja I Berndt *Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA. berndts@mail.nih.gov.ORCID http://orcid.org/0000-0001-5230-0652
Joseph Vijai *Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Yolanda Benavente *Cancer Epidemiology Research Programme, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.
Nicola J Camp *Department of Internal Medicine and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.ORCID http://orcid.org/0000-0002-4788-1998
Alexandra Nieters *Institute for Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Zhaoming Wang *Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0001-7556-3869
Karin E SmedbyDepartment of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Geffen KleinsternSchool of Public Health, University of Haifa, Haifa, Israel.
Henrik HjalgrimDepartment of Epidemiology Research, Division of Health Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-4436-6798
Caroline BessonCentre Hospitalier de Versailles, Le Chesnay, France.ORCID http://orcid.org/0000-0003-4364-7173
Christine F SkibolaDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Lindsay M MortonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.ORCID http://orcid.org/0000-0001-9767-2310
Angela R Brooks-WilsonGenome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada.
Lauren R TerasDepartment of Population Science, American Cancer Society, Atlanta, GA, USA.ORCID http://orcid.org/0000-0003-2419-8536
Charles BreezeDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Joshua AriasDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.ORCID http://orcid.org/0000-0001-6545-6656
Hans-Olov AdamiDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-9592-5791
Demetrius AlbanesDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Kenneth C AndersonDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6418-0886
Stephen M AnsellDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0003-1244-6758
Bryan BassigDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Nikolaus BeckerDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg, Germany.
Parveen BhattiDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Brenda M BirmannChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7550-5498
Paolo BoffettaStony Brook Cancer Center, Stony Brook University, Stony Brook, New York, 11794, NY, USA.
Paige M BracciDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Paul BrennanInternational Agency for Research on Cancer (IARC), Lyon, France.
Elizabeth E BrownDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Laurie BurdettCancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg, MA, USA.
Lisa A Cannon-AlbrightDepartment of Internal Medicine and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Ellen T ChangDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Brian C H ChiuDepartment of Public Health Sciences University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-8979-7244
Charles C ChungDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Jacqueline ClavelCRESS, UMR1153, INSERM, Villejuif, France.
Pierluigi CoccoCentre for Occupational and Environmental Health, Division of Population Science, Health Services Research & Primary Care, University of Manchester, Manchester, United Kingdom.
Graham ColditzDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-7307-0291
Lucia CondeBill Lyons Informatics Centre, UCL Cancer Institute, University College London, London, United Kingdom.
David V ContiDepartment of Population and Public Health Sciences, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
David G CoxINSERM U1052, Cancer Research Center of Lyon, Centre Léon Bérard, Lyon, France.
Karen CurtinDepartment of Internal Medicine and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Delphine CasabonneCancer Epidemiology Research Programme, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.
Immaculata De VivoDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Arjan DiepstraDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
W Ryan DiverDepartment of Population Science, American Cancer Society, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-5418-9000
Ahmet DoganDepartments of Laboratory Medicine and Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0001-6576-5256
Christopher K EdlundDepartment of Population and Public Health Sciences, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Lenka ForetovaDepartment of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
Joseph F FraumeniDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Attilio GabbasDepartment of Public Health, Clinical and Molecular Medicine, University of Cagliari, Monserrato, Cagliari, Italy.
Hervé GhesquièresDepartment of Hematology, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre Benite, France.
Graham G GilesCancer Epidemiology Division, Cancer Council Victoria, Melbourne, VC, Australia.ORCID http://orcid.org/0000-0003-4946-9099
Sally GlaserCancer Prevention Institute of California, Fremont, CA, USA.
Martha GlennDepartment of Internal Medicine and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Bengt GlimeliusDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Jian GuDepartment of Epidemiology, MD Anderson Cancer Center, Houston, TX, USA.ORCID http://orcid.org/0000-0003-3499-0973
Thomas M HabermannDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Christopher A HaimanDepartment of Population and Public Health Sciences, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Corinne HaiounLymphoid Malignancies Unit, Henri Mondor Hospital and University Paris Est, Créteil, France.
Jonathan N HofmannDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.ORCID http://orcid.org/0000-0002-1043-5812
Theodore R HolfordDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Elizabeth A HollyDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Amy HutchinsonCancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg, MA, USA.
Aalin IzharDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Rebecca D JacksonDivision of Endocrinology, Diabetes and Metabolism, The Ohio State University, Columbus, OH, USA.
Ruth F JarrettMRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.ORCID http://orcid.org/0000-0003-0390-3478
Rudolph KaaksDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg, Germany.
Eleanor KaneDepartment of Health Sciences, University of York, York, United Kingdom.ORCID http://orcid.org/0000-0002-7438-9982
Laurence N KolonelCancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA.
Yinfei KongInformation Systems and Decision Sciences, California State University, Fullerton, Fullerton, CA, USA.
Peter KraftDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Anne KrickerSydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.
Annette LakeMRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.
Qing LanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Charles LawrenceWestat, Rockville, MA, USA.
Dalin LiF. Widjaja Family Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Mark LiebowDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Brian K LinkDepartment of Internal Medicine, Carver College of Medicine, The University of Iowa, Iowa City, IA, USA.
Corrado MagnaniCPO-Piemonte and Unit of Medical Statistics and Epidemiology, Department Translational Medicine, University of Piemonte Orientale, Novara, Italy.
Marc MaynadieINSERM U1231, EA 4184, Registre des Hémopathies Malignes de Côte d'Or, University of Burgundy and Dijon University Hospital, Dijon, France.
James McKayInternational Agency for Research on Cancer (IARC), Lyon, France.
Mads MelbyeDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-8264-6785
Lucia MiligiEnvironmental and Occupational Epidemiology Unit, Cancer Prevention and Research Institute (ISPO), Florence, Italy.
Roger L MilneCancer Epidemiology Division, Cancer Council Victoria, Melbourne, VC, Australia.ORCID http://orcid.org/0000-0001-5764-7268
Thierry J MolinaDepartment of Pathology, APHP, Necker and Robert Debré, Université Paris Cité, Institut Imagine, INSERM U1163, Paris, France.
Alain MonnereauCRESS, UMR1153, INSERM, Villejuif, France.
Rebecca MontalvanWestat, Rockville, MA, USA.
Kari E NorthDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Anne J NovakDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-7904-1651
Kenan OnelDonald and Barbara Zucker School of Medicine, Hofstra/Northwell, Hempstead, New York, NY, USA.
Mark P PurdueDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Kristin A RandDepartment of Population and Public Health Sciences, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Elio RiboliSchool of Public Health, Imperial College London, London, United Kingdom.
Jacques RibyDepartment of Epidemiology, School of Public Health and Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Eve RomanDepartment of Health Sciences, University of York, York, United Kingdom.
Gilles SallesDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-9541-8666
Douglas W SborovDepartment of Internal Medicine and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Richard K SeversonDepartment of Family Medicine and Public Health Sciences, Wayne State University, Detroit, MI, USA.
Tait D ShanafeltDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Martyn T SmithDivision of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA, USA.
Alexandra SmithDepartment of Health Sciences, University of York, York, United Kingdom.
Kevin W SongLeukemia/Bone Marrow Transplantation Program, BC Cancer Agency, Vancouver, BC, Canada.
Lei SongCenter for Cancer Research, National Cancer Institute, Frederick, MA, USA.
Melissa C SoutheyCancer Epidemiology Division, Cancer Council Victoria, Melbourne, VC, Australia.
John J SpinelliCancer Control Research, BC Cancer Agency, Vancouver, BC, Canada.
Anthony StainesSchool of Nursing, Psychotherapy and Community Health, Dublin City University, Dublin, Ireland.
Deborah StephensDepartment of Internal Medicine and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Heather J SutherlandLeukemia/Bone Marrow Transplantation Program, BC Cancer Agency, Vancouver, BC, Canada.
Kaitlyn TkachukDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Carrie A ThompsonDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Hervé TillyCentre Henri Becquerel, Université de Rouen, Rouen, France.
Lesley F TinkerDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Ruth C TravisCancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom.
Jenny TurnerFaculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Celine M VachonDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-1962-9322
Claire M VajdicThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-3612-8298
Anke Van Den BergDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-8894-2638
David J Van Den BergDepartment of Population and Public Health Sciences, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Roel C H VermeulenInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Paolo VineisMRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom.
Sophia S WangDivision of Health Analytics, City of Hope Beckman Research Institute, Duarte, CA, USA.
Elisabete WeiderpassInternational Agency for Research on Cancer (IARC), Lyon, France.ORCID http://orcid.org/0000-0003-2237-0128
George J WeinerDepartment of Internal Medicine, Carver College of Medicine, The University of Iowa, Iowa City, IA, USA.
Stephanie WeinsteinDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.ORCID http://orcid.org/0000-0002-3834-1535
Nicole Wong DooConcord Clinical School, University of Sydney, Concord, NSW, Australia.
Yuanqing YeDepartment of Epidemiology, MD Anderson Cancer Center, Houston, TX, USA.
Meredith YeagerDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.ORCID http://orcid.org/0000-0003-3871-2225
Kai YuDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Anne Zeleniuch-JacquotteDepartment of Population Health, New York University School of Medicine, New York, NY, USA.
Yawei ZhangDepartment of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, USA.
Tongzhang ZhengDepartment of Epidemiology, Brown University, Providence, RI, USA.
Elad ZivDivision of General Internal Medicine, Department of Medicine, Institute of Human Genetics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.
Joshua SampsonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Nilanjan ChatterjeeDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
Kenneth OffitDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Wendy CozenChao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA, USA.
Xifeng WuDepartment of Epidemiology, MD Anderson Cancer Center, Houston, TX, USA.
James R CerhanDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-7482-178X
Stephen J ChanockDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.ORCID http://orcid.org/0000-0002-2324-3393
Susan L SlagerDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-5173-4712
Nathaniel RothmanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md, USA.
National Cancer Institute · USInserm · FRMemorial Sloan Kettering Cancer Center · USUniversity of Utah · USMayo Clinic in Arizona · USUniversity of Southern California · USBC Cancer Agency · CACentre international de recherche sur le cancer · FRHarvard University · USMayo Clinic in Florida · USThe University of Melbourne · AUThe University of Texas MD Anderson Cancer Center · USUniversity of California, San Francisco · USUniversity of York · GBAmerican Cancer Society · USBrigham and Women's Hospital · USFred Hutch Cancer Center · USGerman Cancer Research Center · DEInstitut d'Investigació Biomédica de Bellvitge · ESMRC University of Glasgow Centre for Virus Research · GB

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Lila J. Rutten · 1985 to 2026
$151.3M
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MARK Reid PHILIPS · 1985 to 2026
$83.1M
Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, TAMIMI, RULLA M · 2000 to 2019
$77.8M
The Role of Monocytes in non-Hodgkin LymphomaP50CA097274 · NCI · UNIVERSITY OF IOWA · PI HOUTMAN, JON C.D. · 2002 to 2021
$45.7M
Cancer Risk in Human PopulationsZIACP010136 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI PURDUE, MARK · 2009 to 2025
$36.7M
BIOCHEMICAL MARKERS IN THE NURSES'HEALTH STUDY COHORTR01CA049449 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI HANKINSON, SUSAN E · 1989 to 2008
$11.3M
Genetic Epidemiology of Chronic Lymphocytic LeukemiaU01CA118444 · NCI · MAYO CLINIC ROCHESTER · PI SLAGER, SUSAN L · 2006 to 2015
$7.1M
BIOCHEMICAL MARKERS IN THE NURSES HEALTH STUDY COHORTU01CA049449 · NCI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI HANKINSON, SUSAN E · 1995 to 2013
$5.4M
GENETIC EPIDEMIOLOGY OF CHRONIC LYMPHOCYTIC LEUKEMIAR01CA134674 · NCI · UNIVERSITY OF UTAH · PI CAMP, NICOLA J. · 2010 to 2016
$3.8M
A prospective analysis of peripheral blood cytokines and non-Hodgkin lymphomaR01CA149445 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BIRMANN, BRENDA M · 2011 to 2015
$3.0M
Exposure to Organochlorines, EBV, and the Risk of NHLR01CA098122 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI LADEN, FRANCINE · 2003 to 2006
$2.1M
Intramural NIH HHS ZIA CP010136Medical Research Council MC_UU_12014/3Medical Research Council MR/S019669/1NCI NIH HHS K08 CA134919NCI NIH HHS P01 CA087969NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA015083NCI NIH HHS P30 CA016087NCI NIH HHS P50 CA097274NCI NIH HHS R01 CA049449NCI NIH HHS R01 CA098122NCI NIH HHS R01 CA134674NCI NIH HHS R01 CA148690NCI NIH HHS R01 CA149445NCI NIH HHS U01 CA049449NCI NIH HHS U01 CA118444World Health Organization 001
6 · The paper itself

Abstract

Lymphoma risk is elevated for relatives with common non-Hodgkin lymphoma (NHL) subtypes, suggesting shared genetic susceptibility across subtypes. To evaluate the extent of mutual heritability among NHL subtypes and discover novel loci shared among subtypes, we analyzed data from eight genome-wide association studies within the InterLymph Consortium, including 10,629 cases and 9505 controls. We utilized Association analysis based on SubSETs (ASSET) to discover loci for subsets of NHL subtypes and evaluated shared heritability across the genome using Genome-wide Complex Trait Analysis (GCTA) and polygenic risk scores. We discovered 17 genome-wide significant loci (P < 5 × 10

Indexed as

Genetic Predisposition to DiseaseLymphoma, Non-HodgkinCase-Control StudiesGenome-Wide Association StudyGerm CellsHumansPolymorphism, Single NucleotideRisk Factors

Identifiers

PMID36273105
PMCPMC10337695
OpenAlexW4307114719

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.