ArticleScientific reports2022
Communication skills in children aged 6-8 years, without cerebral palsy cooled for neonatal hypoxic-ischemic encephalopathy.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Study protocol of the Speech of children After Neonatal Encephalopathy (SANE): a single-centre prospective cohort study.BMJ open · 2026Article
- CoolCuddle and Autonomic Regulation in Infants With Hypoxic-Ischaemic Encephalopathy: An Intervention Study.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Neonatal Hypoxic-Ischemic Encephalopathy: From the Limitations of Therapeutic Hypothermia to Precision Intervention.Drug design, development and therapy · 2026Review
- Shifting outlooks after neonatal encephalopathy in the era of therapeutic hypothermia.Pediatric research · 2025Review
- Neonatal encephalopathy and hypoxic-ischemic encephalopathy: the state of the art.Pediatric research · 2025Review
- Real-World Therapeutic Hypothermia for Neonatal HIE: Neurodevelopmental Outcomes and Predictors.Acta paediatrica (Oslo, Norway : 1992) · 2025Observational
- Predictors for Development of Asphyxiated Neonates Treated With Therapeutic Hypothermia.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Risk factors for infection and outcomes in infants with neonatal encephalopathy: a cohort study.Pediatric research · 2024Article
- Medicaid unbroken: ensuring continuous United States public health insurance coverage for children to school age.Pediatric research · 2024Article
- The Impact of Time to Initiate Therapeutic Hypothermia on Short-Term Neurological Outcomes in Neonates with Hypoxic-Ischemic Encephalopathy.Children (Basel, Switzerland) · 2024Article
- Resting-state functional connectivity in children cooled for neonatal encephalopathy.Brain communications · 2024Article
- Cerebellar growth, volume and diffusivity in children cooled for neonatal encephalopathy without cerebral palsy.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
We assessed communication skills of 48 children without cerebral palsy (CP) treated with therapeutic hypothermia (TH) for neonatal hypoxic-ischemic encephalopathy (HIE) (cases) compared to 42 controls at early school-age and examined their association with white matter diffusion properties in both groups and 18-month Bayley-III developmental assessments in cases. Parents completed a Children's Communication Checklist (CCC-2) yielding a General Communication Composite (GCC), structural and pragmatic language scores and autistic-type behavior score. GCC ≤ 54 and thresholds of structural and pragmatic language score differences defined language impairment. Using tract-based spatial statistics (TBSS), fractional anisotropy (FA) was compared between 31 cases and 35 controls. Compared to controls, cases had lower GCC (p = 0.02), structural (p = 0.03) and pragmatic language score (p = 0.04) and higher language impairments (p = 0.03). GCC correlated with FA in the mid-body of the corpus callosum, the cingulum and the superior longitudinal fasciculus (p < 0.05) in cases. Bayley-III Language Composite correlated with GCC (r = 0.34, p = 0.017), structural (r = 0.34, p = 0.02) and pragmatic (r = 0.32, p = 0.03) language scores and autistic-type behaviors (r = 0.36, p = 0.01).
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