Evidence map›Paper›PMID 36272817›Full record

ArticleMayo Clinic proceedings2022

Sudden Cardiac Death in Patients With Type 1 Versus Type 2 Diabetes.

Faye L Norby, Kyndaron Reinier, Audrey Uy-Evanado, Gregory A Nichols, Eric C Stecker, Jonathan Jui, Sumeet S Chugh

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mayo Clinic proceedings, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trajectory of Kidney Function in T1D over Time: A Scoping Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
  3. Review
  4. Article
  5. Islet Tissue Macrophages in Immunity Homeostasis and Type 1 Diabetes.Clinical reviews in allergy & immunology · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Faye L NorbyCenter for Cardiac Arrest Prevention, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA.
Kyndaron ReinierCenter for Cardiac Arrest Prevention, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA.
Audrey Uy-EvanadoCenter for Cardiac Arrest Prevention, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA.
Gregory A NicholsKaiser Permanente Center for Health Research, Portland, OR.
Eric C SteckerOregon Health and Science University, Portland, OR.
Jonathan JuiOregon Health and Science University, Portland, OR.
Sumeet S ChughCenter for Cardiac Arrest Prevention, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA. Electronic address: Sumeet.Chugh@csmc.edu.
Cedars-Sinai Smidt Heart Institute · USOregon Health & Science University · USKaiser Permanente Center for Health Research · US

Funding

Prediction of imminent sudden cardiac death based on warning signsR01HL147358 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CHUGH, SUMEET S. · 2020 to 2023
$3.2M
Community-Based Evaluation of Sudden Cardiac Death in Hispanics/LatinosR01HL145675 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CHUGH, SUMEET S. · 2019 to 2023
$2.4M
NHLBI NIH HHS R01 HL145675NHLBI NIH HHS R01 HL147358
6 · The paper itself

Abstract

objectiveTo investigate the association between type 1 diabetes mellitus (T1D) and type 2 diabetes mellitus (T2D) with risk of sudden cardiac arrest (SCA).

methodsIn a prospective community-based study of SCA from February 1, 2002, through November 30, 2019, we ascertained 2771 cases age 18 years of age or older and matched them to 8313 controls based on geography, age, sex, and race/ethnicity. We used logistic regression to evaluate the independent association between diabetes, T1D, T2D, and SCA.

resultsPatients had a mean age of 64.5±15.9 years, were 33.3% female and 23.9% non-White race. Overall, 36.7% (n=1016) of cases and 23.8% (n=1981) of controls had diabetes. Among individuals with diabetes, the proportion of T1D was 6.5% (n=66) among cases and 2.0% among controls (n=40). Diabetes was associated with 1.5-times higher odds of SCA. Compared with those without diabetes, the odds ratio and 95% CI for SCA was 4.36 (95% CI, 2.81 to 6.75; P<.001) in T1D and 1.45 (95% CI, 1.30 to 1.63; P<.001) in T2D after multivariable adjustment. Among those with diabetes, the odds of having SCA were 2.41 times higher in T1D than in T2D (95% CI, 1.53 to 3.80; P<.001). Cases of SCA with T1D were more likely to have an unwitnessed arrest, less likely to receive resuscitation, and less likely to survive compared with those with T2D.

conclusionType 1 diabetes was more strongly associated with SCA compared with T2D and had less favorable outcomes following resuscitation. Diabetes type could influence the approach to risk stratification and prevention of SCA.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Heart ArrestAdolescentAdultAgedAged, 80 and overDeath, Sudden, CardiacFemaleHumansMaleMiddle AgedProspective StudiesRisk Factors

Identifiers

PMID36272817
PMCPMC12424092
OpenAlexW4306955710

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.