Evidence map›Paper›PMID 36272556›Full record

ArticleNeuroscience letters2022

Effects of long-term COVID-19 confinement and music stimulation on mental state and brain activity of young people.

Lina Luo, Mianjia Shan, Yangmin Zu, Yufang Chen, Lingguo Bu, Lejun Wang, Ming Ni, Wenxin Niu

Abstract read
In one paragraph

Article in Neuroscience letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lina LuoShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai 201619, China.
Mianjia ShanShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai 201619, China.
Yangmin ZuShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai 201619, China.
Yufang ChenShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai 201619, China.
Lingguo BuJoint SDU-NTU Centre for Artificial Intelligence Research, Shandong University, Jinan 250101, China.
Lejun WangSport and Health Research Center, Physical Education Department, Tongji University, Shanghai 200092, China.
Ming NiDepartment of Science Development, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Wenxin NiuShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai 201619, China. Electronic address: niu@tongji.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Corona Virus Disease 2019 (COVID-19) pandemic may have had a negative emotional impact on individuals. This study investigated the effect of long-term lockdown and music on young people's mood and neurophysiological responses in the prefrontal cortex (PFC). Fifteen healthy young adults were recruited and PFC activation was acquired using functional near-infrared spectroscopy during the conditions of resting, Stroop and music stimulation. The Depression Anxiety Stress Scales mental scale scores were simultaneously recorded. Mixed effect models, paired t-tests, one-way ANOVAs and Spearman analyses were adopted to analyse the experimental parameters. Stress, anxiety and depression levels increased significantly from Day 30 to Day 40. In terms of reaction time, both Stroop1 and Stroop2 were faster on Day 40 than on Day 30 (P = 0.01, P = 0.003). The relative concentration changes of oxyhemoglobin were significantly higher during premusic conditions than music stimulation and postmusic Stroop. The intensity of functional connectivity shifted from inter- to intracerebral over time. In conclusion, the reduced hemodynamic response of the PFC in healthy young adults is associated with negative emotions, especially anxiety, during lockdown. Immediate music stimulation appears to improve efficiency by altering the pattern of connections in PFC.

Indexed as

COVID-19MusicAdolescentCommunicable Disease ControlHumansPrefrontal CortexSpectroscopy, Near-InfraredYoung AdultCognitive neuroscienceFunctional brain connectivityLockdownMusic stimulationNegative emotionsPrefrontal cortex activation

Identifiers

PMID36272556
PMCPMC9580244

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.