Evidence map›Paper›PMID 36272516›Full record

ArticlePreventive medicine2022

Relating individual differences in the reinforcing value of smoking and dependence severity to nicotine exposure levels in vulnerable populations.

Kaitlyn O Browning, Michael J DeSarno, Danielle R Davis, Joanna M Streck, Cecilia L Bergeria, Roxanne F Harfmann, Maria A Parker, Sarah H Heil, Stacey C Sigmon, Diann E Gaalema and 4 more

Open access · greenAbstract read
In one paragraph

Article in Preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Kaitlyn O BrowningVermont Center on Behavior and Health, University of Vermont, Burlington, VT, United States of America.
Michael J DeSarnoVermont Center on Behavior and Health, University of Vermont, Burlington, VT, United States of America.
Danielle R DavisYale University Tobacco Center of Regulatory Science, Yale University School of Medicine, New Haven, CT, United States of America.
Joanna M StreckDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America.
Cecilia L BergeriaBehavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Roxanne F HarfmannVermont Center on Behavior and Health, University of Vermont, Burlington, VT, United States of America.
Maria A ParkerSchool of Public Health, Indiana University, Bloomington, IN, United States of America.
Sarah H HeilVermont Center on Behavior and Health, University of Vermont, Burlington, VT, United States of America.
Stacey C SigmonVermont Center on Behavior and Health, University of Vermont, Burlington, VT, United States of America.
Diann E GaalemaVermont Center on Behavior and Health, University of Vermont, Burlington, VT, United States of America.
Jennifer W TideyCenter for Alcohol and Addiction Studies, Brown University, Providence, RI, United States of America.
Dustin C LeeBehavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Haley J TetreaultVermont Center on Behavior and Health, University of Vermont, Burlington, VT, United States of America.
Stephen T HigginsVermont Center on Behavior and Health, University of Vermont, Burlington, VT, United States of America. Electronic address: stephen.higgins@uvm.edu.
University of Vermont · USBrown University · USIndiana University Bloomington · USMassachusetts General Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
VERY LOW NICOTINE CIGARETTES IN SMOKERS WITH SCHIZOPHRENIAU54DA031659 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HATSUKAMI, DOROTHY K · 2011 to 2022
$64.7M
Vermont Center on Behavior and HealthP20GM103644 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HIGGINS, STEPHEN T · 2013 to 2022
$21.3M
University of Vermont Tobacco Center of Regulatory ScienceU54DA036114 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HIGGINS, STEPHEN T · 2018 to 2022
$19.4M
Vermont Center on Tobacco Regulatory ScienceP50DA036114 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HIGGINS, STEPHEN T · 2013 to 2017
$19.1M
TRAINING IN BEHAV. PHARMACOLOGY OF HUMAN DRUG DEPENDENCET32DA007242 · NIDA · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI HEIL, SARAH H, HIGGINS, STEPHEN T · 1990 to 2025
$8.2M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS P50 DA036114NIDA NIH HHS T32 DA007242NIDA NIH HHS U54 DA031659NIDA NIH HHS U54 DA036114NIGMS NIH HHS P20 GM103644
6 · The paper itself

Abstract

Cigarette smoking is overrepresented in populations with psychiatric conditions and socioeconomic disadvantage. Greater understanding of the role of reinforcement and nicotine dependence in smoking among vulnerable populations may facilitate development of better targeted interventions to reduce smoking. Prior research demonstrated that individual differences in the reinforcing value of smoking and nicotine-dependence severity predicted total nicotine-exposure in vulnerable populations. The present study uses multivariate regression to address two aims: (1) Quantify the degree to which the reinforcing value of smoking, assessed using the Cigarette Purchase Task (CPT), and dependence severity assessed using the Fagerström Test of Nicotine Dependence and Brief Wisconsin Inventory of Smoking Dependence Motives (B-WISDM) each account for individual differences in cotinine-plus-3'-hydroxycotinine (COT+3HC) levels. (2) Explore whether there is overlap in the variance accounted for by the CTP, FTND, and B-WISDM. Participants were 628 adults with co-morbid psychiatric conditions or socioeconomic disadvantage who smoked daily. The CPT, FTND, and B-WISDM models accounted for 23.76%, 32.45%, and 29.61% of the variance in COT+3HC levels, respectively. Adding CPT to the FTND model failed to increase the variance accounted for and adding it to the B-WISDM model did so by only 1.2% demonstrating considerable overlap in the variance in nicotine exposure levels accounted for by these three instruments. These results provide new knowledge on the relationship between individual differences in the reinforcing value of smoking and nicotine-exposure levels and suggest differences in reinforcing value may underpin a considerable portion of the variance in nicotine exposure accounted for by dependence severity.

Indexed as

Cigarette SmokingTobacco Use DisorderAdultHumansIndividualityNicotineSurveys and QuestionnairesVulnerable PopulationsNicotineBrief Wisconsin inventory of smoking dependence motivesCigarette purchase taskCigarette smokingCotinineCotinine and trans-3′-hydroxycotinineFagerström test for nicotine dependenceNicotineNicotine dependenceReinforcement

Identifiers

PMID36272516
PMCPMC9986960
OpenAlexW4306804755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.