Evidence map›Paper›PMID 36272082›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Isolation and Characterization of Peritoneal Macrophages from Salamanders.

Anthony Sallese, Georgios Tsissios, J Raúl Pérez-Estrada, Arielle Martinez, Katia Del Rio-Tsonis

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 69% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anthony SalleseDepartment of Biology Miami University, Oxford, OH, USA.
Georgios TsissiosDepartment of Biology Miami University, Oxford, OH, USA.
J Raúl Pérez-EstradaDepartment of Biology Miami University, Oxford, OH, USA.
Arielle MartinezDepartment of Biology Miami University, Oxford, OH, USA.
Katia Del Rio-TsonisDepartment of Biology Miami University, Oxford, OH, USA. delriok@miamioh.edu.
Miami University · US

Funding

On Determinants of Lens RegenerationR01EY027801 · NEI · MIAMI UNIVERSITY OXFORD · PI DEL RIO-TSONIS, KATIA · 2017 to 2019
$1.1M
Inflammation is a driver of newt lens regenerationR21EY033916 · NEI · MIAMI UNIVERSITY OXFORD · PI DEL RIO-TSONIS, KATIA · 2022 to 2023
$397k
NEI NIH HHS R01 EY027801NEI NIH HHS R21 EY033916
6 · The paper itself

Abstract

Salamanders have been used as research models for centuries. While they exhibit a wide range of biological features not seen in mammals, none has captivated scientists like their ability to regenerate. Interestingly, axolotl macrophages have emerged as an essential cell population for tissue regeneration. Whether the same is true in other salamanders such as newt species Notophthalmus viridescens, Cynops pyrrhogaster, or Pleurodeles waltl remains to be seen. Unfortunately, regardless of the species, molecular tools to study macrophage function in salamanders are lacking. We propose that the readily available, terminally differentiated peritoneal macrophages from newts or axolotls could be used to validate molecular reagents in the study of macrophage function during tissue regeneration in salamanders.

Indexed as

CaudataMacrophages, PeritonealAnimalsMammalsPleurodelesSalamandridaeAxolotlsCSF1RDetectionIsolationNewtsPeritoneal Macrophage

Identifiers

PMID36272082
PMCPMC13070022
OpenAlexW4307159432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.