ArticleEuropean radiology2023
Fetal 4D flow MRI of the great thoracic vessels at 3 Tesla using Doppler-ultrasound gating: a feasibility study.
Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 23 citations in OpenAlex.
- Establishing the reliability of non-contrast 4D flow in congenital heart disease at 1.5T.Pediatric radiology · 2026Article
- Automatic Respiratory and Bulk Patient Motion Corrected 3D Fetal MRI.Magnetic resonance in medicine · 2026Article
- The role of magnetic resonance imaging in fetal congenital heart disease.Pediatric radiology · 2025Review
- Fetal Cardiovascular Magnetic Resonance: History, Current Status, and Future Directions.Journal of magnetic resonance imaging : JMRI · 2025Review
- Third trimester fetal 4D flow MRI with motion correction.Magnetic resonance in medicine · 2025Article
- Reliability of 4D Flow MRI for Investigation of Fetal Cardiovascular Hemodynamics in the Third Trimester.Radiology. Cardiothoracic imaging · 2024Article
- Article
- The New Frontiers of Fetal Imaging: MRI Insights into Cardiovascular and Thoracic Structures.Journal of clinical medicine · 2024Review
- Myocardial strain assessment in the human fetus by cardiac MRI using Doppler ultrasound gating and feature tracking.European radiology · 2024Article
- Fetal Cardiac MRI Using Doppler US Gating: Emerging Technology and Clinical Implications.Radiology. Cardiothoracic imaging · 2024Review
- Advances in Fetal Cardiac Imaging and Intervention.CJC pediatric and congenital heart disease · 2024Review
- A comparative study of fetal cardiovascular assessment: utilizing Doppler ultrasound gated MRI and echocardiography with detailed analysis using five axial views.Frontiers in cardiovascular medicine · 2024Article
- Structural and functional fetal cardiac imaging using low field (0.55 T) MRI.Frontiers in pediatrics · 2024Article
- Utility of Fetal Cardiac Resonance Imaging in Prenatal Clinical Practice: Current State of the Art.Diagnostics (Basel, Switzerland) · 2023Review
- The current state and potential innovation of fetal cardiac MRI.Frontiers in pediatrics · 2023Review
- Feasibility of fetal cardiac output measurement by phase-contrast magnetic resonance imaging using Doppler ultrasound gating increases with gestational age.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic ResonanceArticle
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo evaluate the feasibility of Doppler-ultrasound (DUS)-gated 4D flow MRI of the fetal great thoracic vessels at 3T in a clinical setting.
methodsSixteen consecutive fetuses (range 30
resultsFetal 4D flow MRI of the great thoracic vessels was successful in 12/16 fetuses (75%) by adopting clinical 4D flow MR protocols in combination with direct fetal cardiac DUS-gating. Four datasets were excluded due to artefacts by fetal movement or maternal breathing. 4D flow MRI-derived time-velocity curves revealed typical arterial blood flow patterns in the aorta. 4D flow quantification was achieved for the pre-defined target regions. Average velocity and flow volume were 21.1 ± 5.2 cm/s and 6.0 ± 3.1 mL/s in the AAo, 24.3 ± 6.7 cm/s and 8.4 ± 3.7 mL/s in the DAo, 21.9 ± 6.4 cm/s and 7.8 ± 4.2 mL/s in the MPA, and 23.4 ± 4.7 cm/s and 5.9 ± 3.6 mL/s in the DA, respectively.
conclusionsCombination of DUS-gating of the fetal heart and 4D flow MRI allows comprehensive visualisation and quantification of haemodynamics in the fetal great thoracic vessels. DUS-gated fetal 4D flow MRI may provide a new diagnostic approach for prenatal assessment of blood flow haemodynamics. KEY POINTS: • Fetal cardiac Doppler-ultrasound (DUS) gating and 4D flow MRI can be successfully combined. • DUS-gated fetal 4D flow MRI allowed visualisation and evaluation of streamline directionality, illustration of blood flow variations, and pulsatile arterial waveforms in the target vessels. • 4D flow MRI-based visualisation and quantification of the fetal great thoracic vessels were successful and flow metrics agreed with echocardiographic reference values.
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