Evidence map›Paper›PMID 36271803›Full record

ArticleClinical anatomy (New York, N.Y.)2023

Connections between postparotid terminal branches of the facial nerve: An immunohistochemistry study.

Paula Martínez-Pascual, Pilar Pérez-Lloret, Eva Maranillo Alcaide, Carlos Sanz-García, Clara Simón de Blas, José Sanudo, Marko Konschake, Andrea Porzionato, Raffaele De Caro, Veronica Macchi

Open access · bronzeAbstract read
In one paragraph

Article in Clinical anatomy (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Paula Martínez-PascualDepartment of Otorhinolaryngology, University Hospital Severo Ochoa, Leganés, Spain.ORCID https://orcid.org/0000-0001-7102-2010
Pilar Pérez-LloretDepartment of Anatomy and Embryology, Complutense University School of Veterinarian, Madrid, Spain.
Eva Maranillo AlcaideDepartment of Human Anatomy and Embryology, Complutense University School of Medicine, Madrid, Spain.ORCID https://orcid.org/0000-0002-8462-064X
Carlos Sanz-GarcíaDepartment of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain.
Clara Simón de BlasDepartment of Computer Sciences and Statistics, Universidad Rey Juan Carlos, Madrid, Spain.
José SanudoDepartment of Human Anatomy and Embryology, Complutense University School of Medicine, Madrid, Spain.
Marko KonschakeDivision of Clinical and Functional Anatomy, Department for Anatomy, Histology and Embryology, Medical University of Innsbruck (MUI), Innsbruck, Austria.ORCID https://orcid.org/0000-0002-9706-7396
Andrea PorzionatoSection of Anatomy, Department of Neuroscience, University of Padova, Padova, Italy.
Raffaele De CaroSection of Anatomy, Department of Neuroscience, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-2307-0277
Veronica MacchiSection of Anatomy, Department of Neuroscience, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0003-2335-6897
Universidad Complutense de Madrid · ESUniversity of Padua · ITHospital Universitario Severo Ochoa · ESInnsbruck Medical University · ATUniversidad Rey Juan Carlos · ES

Funding

Atracción de Talento de la Comunidad Autónoma de Madrid 2019-T1/BMD-13313Atracción de Talento de la Comunidad Autónoma de Madrid PID2020-113299RA-I00
6 · The paper itself

Abstract

It has been assumed that connections between the postparotid terminal branches of the facial nerve are purely motor. However, the nature of their fibers remains unexplored. The aim of this study is to determine whether these connections comprise motor fibers exclusively. In total 17 connections between terminal facial nerve branches were obtained from 13 different facial nerves. Choline acetyltransferase antibody (ChAT) was used to stain the fibers in the connections and determine whether or not all of them were motor. All connections contained ChAT positive and negative fibers. The average number of fibers overall was 287 (84-587) and the average proportion of positive fibers was 63% (37.7%-91.5%). In 29% of the nerves, >75% of the fibers were ChAT+ (strongly positive); in 52.94%, 50%-75% were ChAT+ (intermediately positive); and in 17.65%, <50% were ChAT+ (weakly positive). Fibers traveling inside the postparotid terminal cranial nerve VII branch connections are not exclusively motor.

Indexed as

Choline O-AcetyltransferaseFacial NerveHumansImmunohistochemistryCholine O-Acetyltransferasecholine acetyltransferasefacial nervefacial nerve motor disordersimmunohistochemistrynerve fibers

Identifiers

PMID36271803
PMCPMC10098607
OpenAlexW4307090155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.