ReviewVeterinary medicine and science2022
Research progress on pharmacological effects and new dosage forms of baicalin.
Review in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
22 citing papers in PubMed, 51 citations in OpenAlex.
- Baicalin: A comprehensive review of its molecular mechanisms and pharmacological activities.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Baicalin as a multifunctional flavone glycoside: pharmacological mechanisms, ADME profile, and therapeutic potential.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Article
- Baicalin nano-micelles for dry eye disease: LC-MS/MS method validation, pharmacokinetics and pharmacodynamics in preclinical models.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025Article
- Effects of Dietary Baicalin on Growth Performance, Serum Biochemical Parameters, Liver Health, Intestinal Health, and Microbiota of Yellow Catfish (Animals : an open access journal from MDPI · 2025Article
- UPLC-ESI-QTOF-MS/MS Profiling, Antioxidant, and Cytotoxicity Potentials of Marrubium vulgare L. Extracts: Experimental Analysis and Computational Validation.Chemistry & biodiversity · 2025Article
- Article
- Research Progress on Regulating Autophagy in Traditional Chinese Medicine for the Treatment of Traumatic Brain Injury.ACS omega · 2025Review
- Effects of Dietary Baicalin on Aflatoxin B1-Induced Growth Performance and Liver Health in Ducklings.Animals : an open access journal from MDPI · 2025Article
- Phosphoproteome Reveals the Role of Baicalin in Alleviating rPVL-Induced Cell Cycle Arrest in BMECs.Microorganisms · 2025Article
- Baicalin as a potential candidate for treating systemic sclerosis.Inflammopharmacology · 2025Review
- Baicalin Decreases the LPS-Induced Intestine Inflammatory Responses by ROS/p-ERK/p-P38 Signal Pathways In Vivo and In Vitro.Biomedicines · 2025Article
- Preparation, immunological and pharmacological effects of flavonoids in Scutellariae radix: a review.Frontiers in pharmacology · 2025Review
- Traditional Chinese Medicine targeting the TGF-β/Smad signaling pathway as a potential therapeutic strategy for renal fibrosis.Frontiers in pharmacology · 2025Review
- Natural compounds improve diabetic nephropathy by regulating the TLR4 signaling pathway.Journal of pharmaceutical analysis · 2024Review
- [Baicalin suppresses type 2 dengue virus-induced autophagy of human umbilical vein endothelial cells by inhibiting the PI3K/AKT pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Preparing a novel baicalin-loaded microemulsion-based gel for transdermal delivery and testing its anti-gout effect.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024Article
- Baicalin enhances proliferation and reduces inflammatory-oxidative stress effect in HBMC complementary medicine and therapies · 2024Article
- Protective Effect of Baicalin on Chlorpyrifos-Induced Liver Injury and Its Mechanism.Molecules (Basel, Switzerland) · 2023Article
- Baicalin Exhibits a Protective Effect against Cisplatin-Induced Cytotoxic Damage in Canine Renal Tubular Epithelial Cells.Metabolites · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs a kind of flavonoid, baicalin (C
objectivesThe present review will describe the current understanding of the pharmacological effects of baicalin in the regulation of inflammation, oxidative stress anti-virus and anti-tumour responses.
methodsWe highlight emerging literature that the application in livestock health and performance, the biological activities, the molecular mechanisms and the dosage forms of baicalin by analysing and summarising the main points of the cited literatures.
resultsIt is found that baicalin can improve the functions of multiple physiological systems. Baicalin has a strong anti-inflammatory effect by regulating TLR4-NFκB-MAPK signalling pathway; it also can reduce oxidative stress by regulating Nrf2-Keap1 pathway; it can inhabit many kinds of virus such as influenza virus, respiratory virus, hepacivirus and others; it can also inhibit the growth of tumour cells by blocking the cell cycle or inducing apoptosis; and new dosage forms such as cationic solid lipid nanoparticles, cyclodextrin inclusion complexes or nanocrystalline can be applied to improve the deficiency of baicalin.
conclusionsIn summary, these studies have elucidated a comprehensive report on the anti-inflammatory, anti-oxidant, anti-virus and anti-tumour of baicalin, these findings thus indicated that baicalin can be used effectively to the field of animal production in future when the appropriate dosage form is determined.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.