Evidence map›Paper›PMID 36271455›Full record

ArticleSystematic reviews2022

Patient journey and resources mapping to implement a praziquantel mass drug administration program for children aged 5 years and below in resource-limited settings.

Mhlengi Vella Ncube, Muhubiri Kabuyaya, Moses John Chimbari

Abstract read
In one paragraph

Article in Systematic reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mhlengi Vella NcubeSchool of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa. mhlengivncube@yahoo.com.ORCID 0000-0002-8317-9856
Muhubiri KabuyayaSchool of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Moses John ChimbariSchool of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Funding

National Institute for Health Research 16/136/33
6 · The paper itself

Abstract

backgroundThe early childhood development of millions of children in some low- and medium-income countries may be compromised by schistosomiasis infections contracted at the age of 5 years and below. Currently, there are no standard guidelines for treating schistosomiasis in children that are 5 years and younger using praziquantel (PZQ), the only drug that the World Health Organization (WHO) recommends for treating schistosomiasis. The review is on processes and resources involved in the treatment of schistosomiasis in children aged 5 years and below.

methodsAn electronic search for peer-reviewed articles published in the period from January 2011 to August 2021 was done in the Academic Search Complete, CINAHL with Full Text, Health Source: Nursing/Academic Edition, and MEDLINE databases via EBSCOHost and Google Scholar databases. The search targeted journals that described the treatment of schistosomiasis in children 5 years and below using praziquantel.

resultsThirteen studies met the inclusion criteria. The patient journey for treating schistosomiasis in children aged 5 years old and below using PZQ included the following activities: enrolment of the children into the treatment program; clinical examination; diagnosis; taking anthropometric measurements; feeding the children, making the PZQ palatable to the children; administration of PZQ; and monitoring of side effects. There was also a variation in the resources used to treat children aged 5 and below for schistosomiasis.

conclusionsA PZQ mass drug administration program for children aged 5 years old and below in endemic areas should exclude the diagnosis of schistosomiasis before treatment. The resources required in the treatment process should be affordable, and should not require skills and maintenance resources that are beyond those that are available at the primary healthcare level.

Indexed as

AnthelminticsDrug-Related Side Effects and Adverse ReactionsSchistosomiasisChildChild, PreschoolHumansMass Drug AdministrationPraziquantelAnthelminticsPraziquantelChildrenPatient journey mapPraziquantelPreschoolSchistosomiasisTreatment

Identifiers

PMID36271455
PMCPMC9585827

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.