ArticleMicrobiome2022
Specific metabolites drive the deterministic assembly of diseased rhizosphere microbiome through weakening microbial degradation of autotoxin.
Article in Microbiome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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Who cites it
60 citing papers in PubMed.
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- Synthetic microbial communities derived from native niches enhance the high-temperature adaptability of Pinus yunnanensis seedlings.Environmental microbiome · 2026Article
- Rice roots recruit Bacillus via the secretion of heptadecanoic acid.Nature plants · 2026Article
- Phyllosphere Keystone Beneficial Specialists Enhance Yield in Nutrient Deficiency-Resistant Sorghum Cultivars.Plant, cell & environment · 2026Article
- Metabolome-driven rhizosphere microbiome assembly determining the health of medicinal herb (Angelica sinensis) against root rot.Microbiome · 2026Article
- Research Progress on Rhizosphere Microbiota for Controlling Soil-Borne Diseases: Mechanisms, Applications, and Challenges.Microorganisms · 2026Review
- Plant spatial compartmentalization buffers bacteriome structure and function under antibiotic stress.Scientific reports · 2026Article
- Phosphorus availability drives rhizosphere metabolite-microbial community interactions to modulate cucumber susceptibility to Fusarium wilt.Microbiome · 2026Article
- The Anna Karenina principle in the assembly of plant microbiome under pathogen stress.NPJ biofilms and microbiomes · 2026Article
- Effects of reductive soil disinfestation on the composition of the soil microbial community in degraded facility cucumber.Microbiology spectrum · 2026Article
- Fusarium enrichment alters the soil microbial community and network structure of Brassica crops.Applied microbiology and biotechnology · 2026Article
- Fusarium wilt disease induced changes in the composition and function of the rhizosphere metabolome and microbiome in tobacco plants.Scientific reports · 2026Article
- Phenolic acid biosynthesis is associated with deleterious microbiome changes during Plasmodiophora brassicae-induced clubroot in pakchoi.Microbiome · 2026Article
- Differential Selection Effects of Continuous AITC Fumigation on Soil Microbial Communities and Functions and Identification of Tolerant Strains.Microorganisms · 2026Article
- Enhancing soil citrulline degrading function to mitigate soil-borne Fusarium wilt.Nature communications · 2026Article
- CHD-18 g-modulated Pseudomonas taxa support poplar salt tolerance.The ISME journal · 2026Article
- Article
- Characteristic rhizosphere metabolites of low-cadmium-accumulating rice drive microbially induced soil cadmium speciation transformation.Frontiers in microbiology · 2026Article
- Beyond desalinization: root interactions with halophyteFrontiers in plant science · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProcess and function that underlie the assembly of a rhizosphere microbial community may be strongly linked to the maintenance of plant health. However, their assembly processes and functional changes in the deterioration of soilborne disease remain unclear. Here, we investigated features of rhizosphere microbiomes related to Fusarium wilt disease and assessed their assembly by comparison pair of diseased/healthy sequencing data. The untargeted metabolomics was employed to explore potential community assembly drivers, and shotgun metagenome sequencing was used to reveal the mechanisms of metabolite-mediated process after soil conditioning.
resultsResults showed the deterministic assembly process associated with diseased rhizosphere microbiomes, and this process was significantly correlated to five metabolites (tocopherol acetate, citrulline, galactitol, octadecylglycerol, and behenic acid). Application of the metabolites resulted in a deterministic assembly of microbiome with the high morbidity of watermelon. Furthermore, metabolite conditioning was found to weaken the function of autotoxin degradation undertaken by specific bacterial group (Bradyrhizobium, Streptomyces, Variovorax, Pseudomonas, and Sphingomonas) while promoting the metabolism of small-molecule sugars and acids initiated from another bacterial group (Anaeromyxobacter, Bdellovibrio, Conexibacter, Flavobacterium, and Gemmatimonas). Video Abstract
conclusionThese findings strongly suggest that shifts in a metabolite-mediated microbial community assembly process underpin the deterministic establishment of soilborne Fusarium wilt disease and reveal avenues for future research focusing on ameliorating crop loss due to this pathogen.
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