Evidence map›Paper›PMID 36271347›Full record

ArticleBMC health services research2022

A scoping review of perceptions from healthcare professionals on antipsychotic prescribing practices in acute care settings.

Natalia Jaworska, Stephana J Moss, Karla D Krewulak, Zara Stelfox, Daniel J Niven, Zahinoor Ismail, Lisa D Burry, Kirsten M Fiest

Open access · goldAbstract readScoping Review
In one paragraph

Article in BMC health services research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Natalia JaworskaDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada. njaworsk@ucalgary.ca.ORCID http://orcid.org/0000-0002-2995-5527
Stephana J MossDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.
Karla D KrewulakDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.
Zara StelfoxDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.
Daniel J NivenDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.
Zahinoor IsmailAlberta Health Services, Calgary, AB, Canada.
Lisa D BurryDepartments of Pharmacy and Medicine, Leslie Dan Faculty of Pharmacy, Sinai Health System, University of Toronto, Toronto, Canada.
Kirsten M FiestDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.
Alberta Health Services · CADalhousie University · CAUniversity of Calgary · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntipsychotic medications are frequently prescribed in acute care for clinical indications other than primary psychiatric disorders such as delirium. Unfortunately, they are commonly continued at hospital discharge and at follow-ups thereafter. The objective of this scoping review was to characterize antipsychotic medication prescribing practices, to describe healthcare professional perceptions on antipsychotic prescribing and deprescribing practices, and to report on antipsychotic deprescribing strategies within acute care.

methodsWe searched MEDLINE, EMBASE, PsycINFO, CINAHL, and Web of Science databases from inception date to July 3, 2021 for published primary research studies reporting on antipsychotic medication prescribing and deprescribing practices, and perceptions on those practices within acute care. We included all study designs excluding protocols, editorials, opinion pieces, and systematic or scoping reviews. Two reviewers screened and abstracted data independently and in duplicate. The protocol was registered on Open Science Framework prior to data abstraction (10.17605/OSF.IO/W635Z).

resultsOf 4528 studies screened, we included 80 studies. Healthcare professionals across all acute care settings (intensive care, inpatient, emergency department) perceived prescribing haloperidol (n = 36/36, 100%) most frequently, while measured prescribing practices reported common quetiapine prescribing (n = 26/36, 76%). Indications for antipsychotic prescribing were delirium (n = 48/69, 70%) and agitation (n = 20/69, 29%). Quetiapine (n = 18/18, 100%) was most frequently prescribed at hospital discharge. Three studies reported in-hospital antipsychotic deprescribing strategies focused on pharmacist-driven deprescribing authority, handoff tools, and educational sessions.

conclusionsPerceived antipsychotic prescribing practices differed from measured prescribing practices in acute care settings. Few in-hospital deprescribing strategies were described. Ongoing evaluation of antipsychotic deprescribing strategies are needed to evaluate their efficacy and risk.

Indexed as

Antipsychotic AgentsDeliriumCritical CareDelivery of Health CareHaloperidolHumansQuetiapine FumarateAntipsychotic AgentsHaloperidolQuetiapine FumarateAcute careAntipsychotic medicationsCritical careDeprescribingPrescribing practices

Identifiers

PMID36271347
PMCPMC9587627
OpenAlexW4307090451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.