ArticleNature communications2022
Functional architecture of executive control and associated event-related potentials in macaques.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Laminar architecture of visual and auditory responses in the supplementary eye field of macaques.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Computational and Neuronal Basis of Visual Confidence.Annual review of vision science · 2025Review
- Article
- A preparatory cranial potential for saccadic eye movements in macaque monkeys.bioRxiv : the preprint server for biology · 2025Article
- How Do Common Marmosets Maintain the Balance Between Response Execution and Action Inhibition?American journal of primatology · 2025Article
- Article
- Biophysical Modeling of Frontocentral ERP Generation Links Circuit-Level Mechanisms of Action-Stopping to a Behavioral Race Model.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Clustering the cortical laminae: in vivo parcellation.Brain structure & function · 2024Article
- Conflict detection and resolution in macaque frontal eye fields.Communications biology · 2024Article
- Agranular frontal cortical microcircuit underlying cognitive control in macaques.Frontiers in neural circuits · 2024Review
- Neural mechanisms for executive control of speed-accuracy trade-off.Cell reports · 2023Article
- Cortical origin of theta error signals.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Biophysical modeling of frontocentral ERP generation links circuit-level mechanisms of action-stopping to a behavioral race model.bioRxiv : the preprint server for biology · 2023Article
- Neurophysiological mechanisms of error monitoring in human and non-human primates.Nature reviews. Neuroscience · 2023Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
The medial frontal cortex (MFC) enables executive control by monitoring relevant information and using it to adapt behavior. In macaques performing a saccade countermanding (stop-signal) task, we simultaneously recorded electrical potentials over MFC and neural spiking across all layers of the supplementary eye field (SEF). We report the laminar organization of neurons enabling executive control by monitoring the conflict between incompatible responses, the timing of events, and sustaining goal maintenance. These neurons were a mix of narrow-spiking and broad-spiking found in all layers, but those predicting the duration of control and sustaining the task goal until the release of operant control were more commonly narrow-spiking neurons confined to layers 2 and 3 (L2/3). We complement these results with evidence for a monkey homolog of the N2/P3 event-related potential (ERP) complex associated with response inhibition. N2 polarization varied with error-likelihood and P3 polarization varied with the duration of expected control. The amplitude of the N2 and P3 were predicted by the spike rate of different classes of neurons located in L2/3 but not L5/6. These findings reveal features of the cortical microcircuitry supporting executive control and producing associated ERPs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.