Evidence map›Paper›PMID 36271004›Full record

ArticleNature communications2022

Molecular insights into the distinct signaling duration for the peptide-induced PTH1R activation.

Xiuwen Zhai, Chunyou Mao, Qingya Shen, Shaokun Zang, Dan-Dan Shen, Huibing Zhang, Zhaohong Chen, Gang Wang, Changming Zhang, Yan Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  6. Advances in Parathyroid Hormone-based medicines.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. DimericeLife · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. The Intricacies of Renal Phosphate Reabsorption-An Overview.International journal of molecular sciences · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xiuwen Zhai *National Clinical Research Center of Kidney Diseases, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 211166, Jiangsu, China.ORCID 0000-0001-5205-7429
Chunyou Mao *Center for Structural Pharmacology and Therapeutics Development, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. maochunyou@zju.edu.cn.ORCID 0000-0001-5349-8592
Qingya Shen *Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China.ORCID 0000-0001-6602-7116
Shaokun ZangDepartment of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Dan-Dan ShenDepartment of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huibing ZhangDepartment of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0003-3025-0185
Zhaohong ChenNational Clinical Research Center of Kidney Diseases, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Gang WangNational Clinical Research Center of Kidney Diseases, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 211166, Jiangsu, China.ORCID 0000-0002-9804-2609
Changming ZhangNational Clinical Research Center of Kidney Diseases, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Yan ZhangCenter for Structural Pharmacology and Therapeutics Development, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. zhang_yan@zju.edu.cn.ORCID 0000-0003-2189-0244
Zhihong LiuNational Clinical Research Center of Kidney Diseases, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 211166, Jiangsu, China. liuzhihong@zju.edu.cn.ORCID 0000-0001-6093-0726
Nanjing Medical University · CNSir Run Run Shaw Hospital · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The parathyroid hormone type 1 receptor (PTH1R), a class B1 G protein-coupled receptor, plays critical roles in bone turnover and Ca

Indexed as

Receptor, Parathyroid Hormone, Type 1TeriparatideAmino Acid SequenceCryoelectron MicroscopyLigandsParathyroid HormonePeptidesReceptors, G-Protein-CoupledLigandsParathyroid HormonePeptidesReceptor, Parathyroid Hormone, Type 1Receptors, G-Protein-CoupledTeriparatide

Identifiers

PMID36271004
PMCPMC9586930
OpenAlexW4307138869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.