Evidence map›Paper›PMID 36270714›Full record

ArticleOpen heart2022

Percutaneous left atrial appendage occlusion discrepancy between randomised trials and clinical practice.

Thomas Kümler, Jarl Emanuel Strange, Niels Holmark Andersen

Abstract read
In one paragraph

Article in Open heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Atrial fibrillation: a contemporary update.Clinical medicine (London, England) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thomas KümlerCardiology, Herlev Hospital, Herlev, Denmark tkumler@dadlnet.dk.ORCID 0000-0001-9102-3862
Jarl Emanuel StrangeDepartment of Cardiology, Gentofte Hospital, Hellerup, Denmark.
Niels Holmark AndersenCardiology, Aalborg University Hospital, Aalborg, Denmark.ORCID 0000-0002-5394-3016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with atrial fibrillation and previous episodes of bleeding on oral anticoagulant treatment, left atrial appendage occlusion (LAAO) has emerged as an alternative way to decrease the risk of stroke.The use of the procedure has been on the rise, and the news coverage has been dominated by an uncritical acceptance of the benefit of this procedure, which probably have contributed to the increasing number of procedures.This commentary is a presentation and critical appraisal of the available evidence on the efficacy and safety of left atrial appendage closure as stroke prophylaxis.We illustrate that LAAO is supported by limited randomised data risk of serious complications, which we do not believe supports the current widespread use.

Indexed as

Atrial AppendageAtrial FibrillationCardiac Surgical ProceduresStrokeAnticoagulantsHumansRandomized Controlled Trials as TopicAnticoagulantsAtrial FibrillationEndovascular ProceduresStroke

Identifiers

PMID36270714
PMCPMC9594568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.