Evidence map›Paper›PMID 36270633›Full record

ArticleJournal of medicinal chemistry2022

Discovery and Structure-Activity Relationship Studies of Novel Adenosine A

Barbara Preti, Anna Suchankova, Giuseppe Deganutti, Michele Leuenberger, Kerry Barkan, Iga Manulak, Xianglin Huang, Sabrina Carvalho, Graham Ladds, Martin Lochner

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. QSAR in the Browser: An Interactive Cheminformatics Web Application.Journal of chemical information and modeling · 2026
    Article
  2. Using a NanoBRET-Based Ligand-Binding Assay at the βPharmacology research & perspectives · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Barbara PretiInstitute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012Bern, Switzerland.
Anna SuchankovaDepartment of Pharmacology, University of Cambridge, Tennis Court Road, CambridgeCB2 1PD, U.K.
Giuseppe DeganuttiCentre for Sport, Exercise and Life Sciences, Faculty of Health and Life Sciences, Coventry University, CoventryCV1 5FB, U.K.ORCID 0000-0001-8780-2986
Michele LeuenbergerInstitute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012Bern, Switzerland.ORCID 0000-0003-0641-4338
Kerry BarkanDepartment of Pharmacology, University of Cambridge, Tennis Court Road, CambridgeCB2 1PD, U.K.
Iga ManulakDepartment of Pharmacology, University of Cambridge, Tennis Court Road, CambridgeCB2 1PD, U.K.
Xianglin HuangDepartment of Pharmacology, University of Cambridge, Tennis Court Road, CambridgeCB2 1PD, U.K.
Sabrina CarvalhoDepartment of Pharmacology, University of Cambridge, Tennis Court Road, CambridgeCB2 1PD, U.K.
Graham LaddsDepartment of Pharmacology, University of Cambridge, Tennis Court Road, CambridgeCB2 1PD, U.K.ORCID 0000-0001-7320-9612
Martin LochnerInstitute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012Bern, Switzerland.ORCID 0000-0003-4930-1886
University of Cambridge · GBUniversity of Bern · CHCoventry University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of benzyloxy and phenoxy derivatives of the adenosine receptor agonists

Indexed as

Purinergic P1 Receptor AgonistsReceptors, Purinergic P1AdenosineAdenosine-5'-(N-ethylcarboxamide)AnimalsHalogensHumansRatsStructure-Activity RelationshipAdenosineAdenosine-5'-(N-ethylcarboxamide)HalogensN(6)-cyclopentyl 5'-N-ethylcarboxamidoadenosinePurinergic P1 Receptor AgonistsReceptors, Purinergic P1

Identifiers

PMID36270633
PMCPMC9661479
OpenAlexW4307029515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.