ArticleScience immunology2022
The ZFP36 family of RNA binding proteins regulates homeostatic and autoreactive T cell responses.
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In one paragraph
Article in Science immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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0cells of the map it votes in
72citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
72 citing papers in PubMed, 87 citations in OpenAlex.
- Proximity labeling puts ZFP36L1 as central hub for posttranscriptional regulation networks in T cells.Life science alliance · 2026Article
- Article
- High ZFP36 Family Expression in Exhausted T Cells Is Associated With Impaired Antitumor Effector Function.Cancer science · 2026Article
- Single-cell transcriptomic signatures of T cells associated with rituximab responsiveness in idiopathic nephrotic syndrome.iScience · 2026Article
- Article
- Selective decay of interferon mRNAs controls antiviral immunity and innate memory.Molecular cell · 2026Article
- ZFP36-ferroptosis axis as a key renal protective pathway in diabetic kidney disease.Endocrine journal · 2026Article
- Article
- ZFP36 Family Proteins as Critical Regulators of Inflammation, Immune Cell Development, and Antiviral Responses.Vaccines · 2026Review
- The ZFP36 Family as Post-Transcriptional Regulators in Physiology and Disease.International journal of molecular sciences · 2026Review
- The ZFP36 Family as a Post-Transcriptional Immune Checkpoint in Immunity and Disease: Molecular Mechanisms and Functional Implications.Biomolecules · 2026Review
- Article
- Bioinformatics and Experimental Validation of Diagnostic Marker Genes for Myocardial Infarction and Analysis of Their Immune Cell Infiltration.Biochemical genetics · 2026Article
- T cell dysregulation and remodeling in pediatric obesity and weight loss.bioRxiv : the preprint server for biology · 2026Article
- RNA-binding proteins and ribonucleoproteins as determinants of immunity.Nature reviews. Immunology · 2026Review
- Single-Cell RNA-seq Analysis Reveals Distinct Tumor and Immunosuppressive T-Cell Phenotypes in Patients with CLL Treated with Ibrutinib.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026Article
- RNA binding protein ZFP36L1 promotes ferroptosis in chronic rhinosinusitis by destabilizing CAMK2A mRNA and impairing mitochondrial quality control.Clinical and translational medicine · 2026Article
- ZFP36 Alleviates MASLD Through Facilitating TEAD4 mRNA Degradation After Sleeve Gastrectomy.International journal of molecular sciences · 2026Article
- RNA-binding proteins: a comprehensive review of multifaceted regulatory mechanisms in neuroinflammation and implications in the pathogenesis of neurological disorders.Journal of neuroinflammation · 2026Review
- Characterization of NLRP3 Inflammasome-Associated Hub Genes in the Progression of Diabetic Nephropathy.Immunity, inflammation and disease · 2026Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 2 institutions in 1 country.
Melissa E CookDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-2336-956X
Tara R BradstreetDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-4073-6130
Ashlee M WebberDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-2067-5553
Jongshin KimDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-6339-5220
Andrea SantefordDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-7691-6213
Kevin M HarrisDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-0993-6820
Maegan K MurphyDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-3913-8715
Jennifer TranDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-5339-1218
Nada M AbdallaDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-1326-4908
Elizabeth A SchwarzkopfDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-5942-7103
Suellen C GrecoDivision of Comparative Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Carmen M HalabiDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-4889-8131
Rajendra S ApteDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-2281-2336
Perry J BlackshearSignal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.ORCID 0000-0002-9561-8529
Brian T EdelsonDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-2856-7650
Washington University in St. Louis · USNational Institutes of Health · US
Funding
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0MWU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8MWASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Philip Raymond Williams · 1985 to 2026
$18.4MTRAINING PROGRAM IN IMMUNOLOGY AND IMMUNOGENETICST32AI007163 · NIAID · WASHINGTON UNIVERSITY · PI Kenneth M Murphy, Kodi S Ravichandran · 1985 to 2026
$14.8MStanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0MTHE IMPORTANCE OF MACROPHAGE SENESCENCE IN REGULATING ANGIOGENESIS IN THE EYER01EY019287 · NEI · WASHINGTON UNIVERSITY · PI APTE, RAJENDRA S · 2010 to 2021
$3.9MUNDERSTANDING AUTOREACTIVE T CELL PATHOGENICITYR01AI113118 · NIAID · WASHINGTON UNIVERSITY · PI EDELSON, BRIAN TODD · 2015 to 2019
$1.9MElucidating the role of EOMES in Memory-Like NK cell DifferentiationF31GM146361 · NIGMS · WASHINGTON UNIVERSITY · PI TRAN, JENNIFER · 2022 to 2024
$90kNCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NEI NIH HHS P30 EY002687NEI NIH HHS P30 EY026877NEI NIH HHS R01 EY019287NIAID NIH HHS R01 AI113118NIAID NIH HHS T32 AI007163NIGMS NIH HHS F31 GM146361
Abstract
RNA binding proteins are important regulators of T cell activation, proliferation, and cytokine production. The zinc finger protein 36 (ZFP36) family genes (
Indexed as
Granulocyte-Macrophage Colony-Stimulating FactorT-LymphocytesTristetraprolinAnimalsCytokinesHomeostasisMiceRNA-Binding ProteinsCytokinesGranulocyte-Macrophage Colony-Stimulating FactorRNA-Binding ProteinsTristetraprolinZfp36 protein, mouse
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.