Evidence map›Paper›PMID 36269748›Full record

ArticlePloS one2022

Bedside medication review with cognitive and depression screening by a clinical pharmacist as part of a comprehensive geriatric assessment in hospitalized older patients with polypharmacy: A pilot study.

Veerle Mertens, Leen Jacobs, Nicole Knops, Seyedeh Malihe Alemzadeh, Kay Vandeven, Jo Swartenbroekx, Greta Moorkens, Maurits Vandewoude

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Veerle MertensDepartment Geriatrics, Antwerp University Hospital, Antwerp, Belgium.ORCID 0000-0003-2836-2794
Leen JacobsFaculty Pharmacy, University of Antwerp, Antwerp, Belgium.
Nicole KnopsFaculty Political and Social Sciences, Department Management, Belgium and University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Seyedeh Malihe AlemzadehDepartment Pharmacy, General Hospital Sint Jozef Malle, Malle, Belgium.
Kay VandevenDepartment Pharmacy, Antwerp University Hospital, Antwerp, Belgium.
Jo SwartenbroekxDepartment Pharmacy, Antwerp University Hospital, Antwerp, Belgium.
Greta MoorkensDepartment Internal Medicine, Antwerp University Hospital, Antwerp, Belgium.
Maurits VandewoudeDepartment Geriatrics, Antwerp University Hospital, Antwerp, Belgium.
Antwerp University Hospital · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolypharmacy is highly prevalent in older patients with multimorbidity and is associated with increased risk of adverse drug events. This pilot study investigated the added value of a bedside medication review with cognitive and depression screening by a clinical pharmacist to identify potentially inappropriate medications (PIMs) and medication use issues in older patients with polypharmacy. METHODS AND

resultsIn the period from September 2018 to March 2019, a clinical pharmacist took part in the comprehensive geriatric assessment of 37 older patients hospitalized at Antwerp University Hospital and conducted a medication review consisting of a record review, a bedside interview questionnaire covering medication use, evaluation of cognitive function (abbreviated MMSE), depression (GDS-4), and systematic check for possible PIMs (STOPP/START criteria). Patients were 83±4 years old and on a median of 12 home medications (range 5-20). The clinical pharmacist formulated an average of 7.7 recommendations to optimize medication use per patient, of which 89.9% were considered clinically relevant by the geriatrician. Only 2 out of 286 PIMs were discovered during routine electronic validation of medication prescriptions. Supervision of medication intake was absent in 75% of cognitively impaired patients, but advice to do so was implemented in 86.4% of cases. The multidisciplinary geriatric advice was communicated to the treating physician, who fully implemented 33.8% of the recommendations.

conclusionsBedside medication review with cognitive and depression screening by a clinical pharmacist is useful to discover polypharmacy related problems and medication intake issues in a population of geriatric patients. Systematic screening for cognitive impairment and depression are needed to detect patients in need of support for correct medication use and therapy compliance.

Indexed as

PharmacistsPolypharmacyAgedAged, 80 and overCognitionDepressionGeriatric AssessmentHumansInappropriate PrescribingMedication ReviewPilot ProjectsPotentially Inappropriate Medication List

Identifiers

PMID36269748
PMCPMC9586415
OpenAlexW4307009074

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.