Evidence map›Paper›PMID 36269452›Full record

ArticleCurrent microbiology2022

The Combination of Salmonella Phage ST-3 and Antibiotics to Prevent Salmonella Typhimurium In Vitro.

Min Lu, Bingxin Liu, Wenbin Xiong, Xinchun Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Min LuCollege of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 101408, China.
Bingxin LiuCollege of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 101408, China.
Wenbin XiongCollege of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 101408, China.
Xinchun LiuCollege of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 101408, China. xcliu@ucas.ac.cn.

Funding

Fundamental Research Funds for Central Universities of the Central South University E1E40506National Key Laboratory of Science, Technology on Advanced Composites in Special Environments, HIT GYY-DTFZ-2022-008
6 · The paper itself

Abstract

The novel phage ST-3, capable of infecting the foodborne pathogen Salmonella Typhimurium, was isolated from wastewater. The Biological characters and genome information of ST-3 were analyzed. In the in vitro assay, the phage ST-3 with a MOI of 10 effectively inhibited the growth of Salmonella Typhimurium CGMCC 1.1174 in 6 h. The inhibitory effect of combination phage ST-3 and antibiotics was also studied, the removal rate of planktonic host exposed to ST-3 and levofloxacin hydrochloride at the same time, or to ciprofloxacin followed by ST-3, is higher than that exposed to antibiotic dosing group alone and antibiotic + phage dosing group. The phage ST-3 combined with 0.5 µg/mL levofloxacin hydrochloride resulted in the largest decrease in biofilm biomass at 54%. The phage ST-3 could be a potential agent to control Salmonella Typhimurium growth and provide instruction for use it and antibiotics together.

Indexed as

BacteriophagesSalmonella PhagesAnti-Bacterial AgentsCiprofloxacinLevofloxacinMyoviridaeSalmonella typhimuriumWastewaterAnti-Bacterial AgentsCiprofloxacinLevofloxacinWastewater

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.