Evidence map›Paper›PMID 36269442›Full record

Observational studyInternational ophthalmology2023

Clinical observations of corneal topographic and tomographic changes in congenital ptosis eyes: a study in China.

Jianqin Shen, Huiyan Li, Yanhong Chen, Lan Liu, Hongguang Cui

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jianqin ShenDepartment of Ophthalmology, First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No. 79, Hangzhou, 310003, People's Republic of China.
Huiyan LiDepartment of Ophthalmology, First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No. 79, Hangzhou, 310003, People's Republic of China.
Yanhong ChenDepartment of Ophthalmology, First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No. 79, Hangzhou, 310003, People's Republic of China.
Lan LiuDepartment of Ophthalmology, First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No. 79, Hangzhou, 310003, People's Republic of China.
Hongguang CuiDepartment of Ophthalmology, First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No. 79, Hangzhou, 310003, People's Republic of China. 1189002@zju.edu.cn.ORCID http://orcid.org/0000-0001-7311-0188
Hangzhou First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the impact of drooping eyelid on corneal topographic and tomographic alterations in congenital ptosis eyes.

methodsSeventeen Chinese patients with unilateral congenital ptosis were included in this observational study. Ptosis eyes were included in the ptosis group, while normal contralateral eyes were included in the control group. The marginal reflex distance (MRD) was used to evaluate the severity of ptosis. Topographic and tomographic parameters measured by Pentacam, including keratometric, pachymetric, volumetric parameters as well as topometric indexes and D indexes, were recorded and compared between the ptosis group and the control group. Furthermore, correlation analyses were made between MRD and all measured corneal parameters.

resultsThe value of anterior K1, Km and posterior K2, Km was significantly decreased in the ptosis eyes (p < 0.05). Corneal thickness at the pupil center point and thinnest point was significantly thicker in ptosis group compared with the ones in control group (p < 0.05). Higher ISV, IVA, KI, IHD values were observed in ptosis eyes (p < 0.05). The intergroup difference in MRD showed significant correlation with the difference in ISV (p < 0.05).

conclusionThe whole corneal contour is remodeled to be "flatter" in ptosis eyes. The upper eyelid position was closely associated with the corneal irregularity in ptosis eyes. The reasons for the discrepancy in corneal topography and tomography between ptotic and normal eyes were complicated.

Indexed as

BlepharoptosisKeratoconusChinaCorneaCorneal PachymetryCorneal TopographyHumansTomographyCorneaMarginal reflex distancePentacamPtosisTopography

Identifiers

PMID36269442
OpenAlexW4307033658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.