Evidence map›Paper›PMID 36269434›Full record

ArticleCurrent microbiology2022

Study of the Antimicrobial Potential of Actinomycetes Isolated from Organic and Inorganic Waste.

Ines Trabelsi, Raya Soltane, Mouna Hassine-Zaafrane, Ahlam Alasiri, Bander Albogami, Mohamed Nour

Abstract read
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In one paragraph

Article in Current microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ines TrabelsiResearch Laboratory "Bioressources: Biologie Intégrative & Valorisation" BIOLIVAL, Higher Institute of Biotechnology of Monastir, University of Monastir, Avenue Taher Hadded, (BP 74), 5000, Monastir, Tunisia. ines.trabelsi85@gmail.com.ORCID http://orcid.org/0000-0001-5844-6134
Raya SoltaneDepartement of Basic Sciences, Adham University, College, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Mouna Hassine-ZaafraneResearch Unit UR17ES30 "Genomics, Biotechnology and Antiviral Strategies," Higher Institute of Biotechnology of Monastir, University of Monastir, Monastir, Tunisia.
Ahlam AlasiriDepartement of Basic Sciences, Adham University, College, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Bander AlbogamiDepartment of Biology, College of Sciences, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
Mohamed NourResearch Laboratory "Bioressources: Biologie Intégrative & Valorisation" BIOLIVAL, Higher Institute of Biotechnology of Monastir, University of Monastir, Avenue Taher Hadded, (BP 74), 5000, Monastir, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main objective of this investigation was to characterize a collection of actinomycetes strains isolated from unexplored polluted ecosystems and to evaluate their antimicrobial potential in order to discover interesting bioactive compounds. Based on morphological and culture characters, 32 different strains were isolated: 20 strains from compost heap, seven strains from manure, and five strains from waste water. As expected, the genus Streptomyces was the most prevalent followed by the genus Micromonospora. Analysis of the antimicrobial activities of the isolated strains showed that those from compost heap were more efficient against the tested microorganisms (Candida albicans, Methicillin-resistant Staphylococcus aureus, Staphylococcus aureus, Acinetobacter baumannii, Pseudomonas aeruginosa, and Escherichia coli). Several bioactive compounds were identified by liquid chromatography (LC) combined with mass spectrometry (MS) and then analyzed by both MEDINA's database, which contains the most common secondary metabolites, and Dictionary of Natural Products Chapman & Hall. Many interesting well-known and unknown biomolecules were identified. Quinomycin A and Daidzein were the most fascinating compounds isolated, respectively, by Streptomyces sp. WW2 and Streptomyces sp. WW4. The most active strain was identified based on 16S rDNA's sequences and it seems to be a new strain. The crude extract of the strain CH12 was analyzed and the UV absorption spectra and mass spectra (MS) of the main active compound were reported. It's an interesting compound (possible purpuromycin) with the molecular formula C26H18O13.

Indexed as

ActinobacteriaAnti-Infective AgentsBiological ProductsEchinomycinMethicillin-Resistant Staphylococcus aureusStreptomycesActinomycesAnti-Bacterial AgentsDNA, RibosomalEcosystemManureMicrobial Sensitivity TestsRNA, Ribosomal, 16SWastewaterAnti-Bacterial AgentsAnti-Infective AgentsBiological ProductsDNA, RibosomalEchinomycinManureRNA, Ribosomal, 16SWastewater

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.