Evidence map›Paper›PMID 36269402›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

The influence of the topographic location of geographic atrophy on vision-related quality of life in nonexudative age-related macular degeneration.

Aneesha Ahluwalia, Liangbo L Shen, Yihan Bao, Mengyuan Sun, Benjamin K Young, Michael M Park, Lucian V Del Priore

Abstract read
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Visual functioning and geographic atrophy imaging characteristics in age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Aneesha AhluwaliaDepartment of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
Liangbo L ShenDepartment of Ophthalmology, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Yihan BaoDepartment of Statistics and Data Science, Yale University, New Haven, CT, USA.
Mengyuan SunInstitute of Cardiovascular Diseases, Gladstone Institute, San Francisco, CA, USA.
Benjamin K YoungKellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA.
Michael M ParkDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Lucian V Del PrioreDepartment of Ophthalmology and Visual Science, Yale School of Medicine, 40 Temple Street, Suite 1B, New Haven, CT, USA. lucian.delpriore@yale.edu.
Yale University · USGladstone Institutes · USNew York Eye and Ear Infirmary · USStanford University · USUniversity of California, San Francisco · USUniversity of Michigan–Ann Arbor · US

Funding

WASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Steven Bassnett · 1985 to 2026
$18.4M
NIA Short Term Research Training: Students in Health Professional SchoolsT35AG049685 · NIA · YALE UNIVERSITY · PI Sarwat I Chaudhry, Terri R. Fried · 2016 to 2026
$804k
NEI NIH HHS P30 EY02687NIA NIH HHS T35AG049685
6 · The paper itself

Abstract

purposeTo examine associations between the topographic distribution of geographic atrophy (GA) and vision-related quality of life (VRQoL).

methodsThis study included 237 eyes from 161 participants in the Age-Related Eye Disease Study (AREDS). GA lesions were manually delineated with color fundus photographs obtained by the AREDS Research Group and atrophic area was measured in an Early Treatment Diabetic Retinopathy Study (ETDRS) grid. VRQoL was measured using the National Eye Institute Visual Function Questionnaire (NEI-VFQ). Area of atrophy in the ETDRS grid subfields was correlated with VRQoL by linear regression modeling.

resultsThe average area of atrophy in the better and worse eye was 3.43mm

conclusionIn patients with GA, greater area of atrophy in the central 1-mm-diameter zone of the better eye was independently associated with lower VRQoL, while total area of atrophy in the better or worse eye was not.

Indexed as

Diabetic RetinopathyGeographic AtrophyAtrophyHumansQuality of LifeSurveys and QuestionnairesVision, OcularVisual AcuityAge-related macular degenerationArea of atrophyGeographic atrophyTopographic distributionVision-related quality of life

Identifiers

PMID36269402
OpenAlexW3177770249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.