Evidence map›Paper›PMID 36269371›Full record

ArticleEuropean radiology2023

Evaluating prostate cancer bone metastasis using accelerated whole-body isotropic 3D T1-weighted Dixon MRI with compressed SENSE: a feasibility study.

Zhenhong Liao, Gaoyuan Liu, Bing Ming, Chun Ma, Xigang Fan, Xiaoyong Zhang, Wei Peng, Chen Liu

Abstract read
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In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhenhong LiaoDepartment of Radiology, Deyang People's Hospital, 173 Taishan North Road, Jingyang District, Deyang City, Sichuan Province, China.ORCID https://orcid.org/0000-0002-6810-8304
Gaoyuan LiuDepartment of Radiology, Deyang People's Hospital, 173 Taishan North Road, Jingyang District, Deyang City, Sichuan Province, China.
Bing MingDepartment of Radiology, Deyang People's Hospital, 173 Taishan North Road, Jingyang District, Deyang City, Sichuan Province, China. deyanghospital120@163.com.
Chun MaDepartment of Radiology, Deyang People's Hospital, 173 Taishan North Road, Jingyang District, Deyang City, Sichuan Province, China.
Xigang FanDepartment of Radiology, Deyang People's Hospital, 173 Taishan North Road, Jingyang District, Deyang City, Sichuan Province, China.
Xiaoyong ZhangClinical Science, Philips Healthcare, Chengdu, China.
Wei PengDepartment of Radiology, Deyang People's Hospital, 173 Taishan North Road, Jingyang District, Deyang City, Sichuan Province, China.
Chen LiuDepartment of Radiology, Deyang People's Hospital, 173 Taishan North Road, Jingyang District, Deyang City, Sichuan Province, China.
Deyang Stomatological Hospital · CNPhilips (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe study aimed to assess the efficiency of whole-body high-resolution compressed sensing-sensitivity encoding isotropic T1-Weighted Dixon (CSI-T1W-Dixon) scans in evaluating bone metastasis.

methodsForty-five high-risk prostate cancer patients with bone metastases were enrolled prospectively and underwent whole-body MRI sequences, which included the following: pre- and post-contrast CSI-T1W-Dixon and conventional multi-planar T1-Weighted Dixon (CMP-T1W-Dixon) (coronal, sagittal, and axial scans), short tau inversion recovery (STIR), and DWI. Comparison between the CMP-T1W-Dixon and CSI-T1W-Dixon images was done for the subjective image quality, the quantitative contrast-to-noise ratio (CNR), and signal-to-noise ratio (SNR). Furthermore, the diagnostic performance based on per-lesion and per-patient basis utilizing non-contrast T1-weighted (T1)/T1+ contrasted T1-weighted (T1C)/T1 + T1C + STIR + DWI sequences was compared between the CSI-T1W-Dixon and CMP-T1W-Dixon methods using reference standards (combining biopsy data and 6-month imaging follow-up).

resultThe CSI-T1W-Dixon images produced fewer image artifacts in the axial and coronal planes compared to the CMP-T1W-Dixon images. Also, the CSI-T1W-Dixon images provided better a CNR in fat-only images of all three planes and water-only images of the axial plane (p < 0.05). The CSI-T1W-Dixon showed a higher sensitivity than the CMP-T1W-Dixon techniques in analyzing T1-only images on a per-lesion basis (82.7% vs. 53.8% for sensitivity, p = 0.03). On a per-patient basis, no difference was found in the diagnostic capacity between the CSI-T1W-Dixon and CMP-T1W-Dixon sequences either alone or in combinations (p = 0.57-1).

conclusionHigh-resolution CSI-T1W-Dixon with higher image quality and diagnostic capacity can replace the CMP-T1W-Dixon method in evaluating bone metastasis in clinical practice. KEY POINTS: • Compressed sensing isotropic acquisition for 3D T1-weighted Dixon images can improve the image quality with fewer artifacts compared to the anisotropic multiplanar acquisition. • Compressed sensing isotropic acquisition can save 67% of scanning time compared to anisotropic multiplanar acquisition. • Compressed sensing isotropic 3D T1-weighted Dixon images can offer better diagnostic performance with higher sensitivity compared to anisotropic multiplanar images.

Indexed as

Magnetic Resonance ImagingProstatic NeoplasmsFeasibility StudiesHumansImaging, Three-DimensionalMaleSignal-To-Noise RatioBone metastasisCompressed sensingProstate cancerWhole-body imaging

Identifiers

PMID36269371
OpenAlexW4306953128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.