Evidence map›Paper›PMID 36269199›Full record

ArticleHuman brain mapping2023

An artificial-intelligence-based age-specific template construction framework for brain structural analysis using magnetic resonance images.

Dongdong Gu, Feng Shi, Rui Hua, Ying Wei, Yufei Li, Jiayu Zhu, Weijun Zhang, Han Zhang, Qing Yang, Peiyu Huang and 16 more

Open access · goldAbstract read
In one paragraph

Article in Human brain mapping, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 8 institutions in 1 country.

Dongdong GuShanghai United Imaging Intelligence Co., Ltd., Shanghai, China.ORCID 0000-0002-0056-2981
Feng ShiShanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Rui HuaShanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Ying WeiShanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Yufei LiSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0002-3449-6839
Jiayu ZhuShanghai United Imaging Healthcare Co., Ltd., Shanghai, China.
Weijun ZhangShanghai United Imaging Healthcare Co., Ltd., Shanghai, China.
Han ZhangSchool of Biomedical Engineering, ShanghaiTech University, Shanghai, China.
Qing YangSchool of Biomedical Engineering, ShanghaiTech University, Shanghai, China.
Peiyu HuangDepartment of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0003-4226-9369
Yi JiangInstitute of Brain-Intelligence Technology, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai Center of Brain-Intelligence Engineering, Shanghai, China.
Bin BoSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Yao LiSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Yaoyu ZhangSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Minming ZhangDepartment of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0003-0145-7558
Jinsong WuGlioma Surgery Division, Neurologic Surgery Department, Huashan Hospital, Shanghai, China.
Hongcheng ShiDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Siwei LiuDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Qiang HeShanghai United Imaging Healthcare Co., Ltd., Shanghai, China.
Qiang ZhangShanghai United Imaging Healthcare Co., Ltd., Shanghai, China.
Xu ZhangInstitute of Brain-Intelligence Technology, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai Center of Brain-Intelligence Engineering, Shanghai, China.
Hongjiang WeiSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Guocai LiuHunan University, Changsha, China.
Zhong XueShanghai United Imaging Intelligence Co., Ltd., Shanghai, China.ORCID 0000-0003-3207-0890
Dinggang ShenShanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Consortium of Chinese Brain Molecular and Functional Mapping (CBMFM)
United Imaging Healthcare (China) · CNShanghai Jiao Tong University · CNShanghaiTech University · CNCenter for Excellence in Brain Science and Intelligence Technology · CNSecond Affiliated Hospital of Zhejiang University · CNSun Yat-sen University · CNHunan University · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is an essential task to construct brain templates and analyze their anatomical structures in neurological and cognitive science. Generally, templates constructed from magnetic resonance imaging (MRI) of a group of subjects can provide a standard reference space for analyzing the structural and functional characteristics of the group. With recent development of artificial intelligence (AI) techniques, it is desirable to explore AI registration methods for quantifying age-specific brain variations and tendencies across different ages. In this article, we present an AI-based age-specific template construction (called ASTC) framework for longitudinal structural brain analysis using T1-weighted MRIs of 646 subjects from 18 to 82 years old collected from four medical centers. Altogether, 13 longitudinal templates were constructed at a 5-year age interval using ASTC, and tissue segmentation and substructure parcellation were performed for analysis across different age groups. The results indicated consistent changes in brain structures along with aging and demonstrated the capability of ASTC for longitudinal neuroimaging study.

Indexed as

Artificial IntelligenceBrainAdolescentAdultAgedAged, 80 and overAge FactorsHumansImage Processing, Computer-AssistedIntelligenceMagnetic Resonance ImagingMiddle AgedYoung Adultartificial intelligencebrain templatelongitudinal templatemagnetic resonance imaging (MRI)registrationstatistical analysis

Identifiers

PMID36269199
PMCPMC9875934
OpenAlexW4307033484

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.