Evidence map›Paper›PMID 36269166›Full record

ArticleHuman brain mapping2023

Reversal of neurovascular decoupling and cognitive impairment in patients with end-stage renal disease during a hemodialysis session: Evidence from a comprehensive fMRI analysis.

Peng Li, Shaohui Ma, Xueying Ma, Dun Ding, Xinyi Zhu, Huawen Zhang, Jixin Liu, Junya Mu, Ming Zhang

Open access · goldAbstract read
In one paragraph

Article in Human brain mapping, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

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  9. Genetic and circulating biomarkers of cognitive dysfunction and dementia in CKD.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Peng LiDepartment of Medical Imaging, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Shaohui MaDepartment of Medical Imaging, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Xueying MaDepartment of Medical Imaging, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, China.
Dun DingDepartment of Medical Imaging, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Xinyi ZhuDepartment of Medical Imaging, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Huawen ZhangDepartment of Medical Imaging, Nuclear Industry 215 Hospital of Shaanxi Province, Xianyang, Shaanxi, China.ORCID 0000-0001-8165-7917
Jixin LiuCenter for Brain Imaging, School of Life Science and Technology, Xidian University, Xi'an, China.
Junya MuDepartment of Medical Imaging, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID 0000-0002-5135-1156
Ming ZhangDepartment of Medical Imaging, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID 0000-0002-6546-2762
First Affiliated Hospital of Xi'an Jiaotong University · CNInner Mongolia Medical University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CNXian Yang Central Hospital · CNXidian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurovascular (NV) decoupling is a potential neuropathologic mechanism of cognitive impairment in patients with end-stage renal disease (ESRD). Hemodialysis improves cognitive impairment at 24 h post-dialysis, which suggests a potential neuroprotective effect of hemodialysis treatment on the brain. We investigated the effects of hemodialysis treatment on the reversal of NV decoupling associated with cognitive improvement. A total of 39 patients with ESRD and 39 healthy controls were enrolled. All patients were imaged twice during a dialysis session: before hemodialysis (T1

Indexed as

Cognitive DysfunctionKidney Failure, ChronicBrainHumansMagnetic Resonance ImagingRenal Dialysisarterial spin labelingend-stage renal diseasehemodialysisneurovascular couplingresting-state functional magnetic resonance imaging

Identifiers

PMID36269166
PMCPMC9875915
OpenAlexW4307032577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.