Evidence map›Paper›PMID 36268985›Full record

ArticleJournal of clinical laboratory analysis2022

Clinical features of patients with talaromycosis marneffei and microbiological characteristics of the causative strains.

Lei Peng, Yu-Bo Shi, Lin Zheng, Li-Qing Hu, Xing-Bei Weng

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Cardiovascular system characteristics in HIV/AIDS patients with talaromycosis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  4. Review
  5. Mechanisms ofVirulence · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lei PengSchool of Medicine, Ningbo University, Ningbo, China.
Yu-Bo ShiDepartment of Medical Laboratory, Ningbo First Hospital, Ningbo, China.
Lin ZhengDepartment of Medical Laboratory, The Affiliated Hospital of Medical School of Ningbo University, Ningbo, China.
Li-Qing HuDepartment of Medical Laboratory, Ningbo First Hospital, Ningbo, China.
Xing-Bei WengSchool of Medicine, Ningbo University, Ningbo, China.ORCID https://orcid.org/0000-0001-8893-1704
Ningbo University · CNNingbo First Hospital · CN

Funding

Natural Science Foundation of Ningbo 2019A610381Ningbo Public Welfare Foundation 2019C50087
6 · The paper itself

Abstract

backgroundTalaromyces marneffei (T. marneffei) is a temperature-dependent dimorphic fungus that is mainly prevalent in Southeast Asia and South China and often causes disseminated life-threatening infections. This study aimed to investigate the clinical features and improve the early diagnosis of talaromycosis marneffei in nonendemic areas.

methodsWe retrospectively analyzed the medical records of six cases of T. marneffei infection. We describe the clinical manifestations, laboratory tests, and imaging manifestations of the six patients.

resultsTalaromyces marneffei infection was confirmed by sputum culture, blood culture, tissue biopsy, and metagenomic next-generation sequencing (mNGS). In this study, there were five disseminated-type patients and two HIV patients. One patient died within 24 h, and the others demonstrated considerable improvement after definitive diagnosis.

conclusionsDue to the lack of significant clinical presentations of talaromycosis marneffei, many cases may be easily misdiagnosed in nonendemic areas. It is particularly important to analyze the imaging manifestations and laboratory findings of infected patients. With the rapid development of molecular biology, mNGS may be a rapid and effective diagnostic method.

Indexed as

HIV InfectionsMycosesAntifungal AgentsChinaHumansRetrospective StudiesAntifungal Agentsdisseminated Talaromyces marneffei infectionlaboratory testmetagenomic next-generation sequencingTalaromyces marneffeitalaromycosis marneffei

Identifiers

PMID36268985
PMCPMC9701894
OpenAlexW4306986086

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.