Evidence map›Paper›PMID 36268894›Full record

ArticleAmerican journal of industrial medicine2022

End-stage renal disease incidence in a cohort of US firefighters from San Francisco, Chicago, and Philadelphia.

Lynne E Pinkerton, Stephen Bertke, Matthew M Dahm, Travis L Kubale, Miriam R Siegel, Thomas R Hales, James H Yiin, Mark P Purdue, James J Beaumont, Robert D Daniels

Open access · hybridAbstract read
In one paragraph

Article in American journal of industrial medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Lynne E PinkertonMaximus, McLean, Virginia, USA.ORCID 0000-0002-8669-487X
Stephen BertkeDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.ORCID 0000-0002-3047-3816
Matthew M DahmDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Travis L KubaleWorld Trade Center Health Program, National Institute for Occupational Safety and Health, Washington, District of Columbia, USA.
Miriam R SiegelDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.ORCID 0000-0002-0231-2564
Thomas R HalesDivision of Safety Research, National Institute for Occupational Safety and Health, Denver, Colorado, USA.
James H YiinOffice of Extramural Programs, National Institute for Occupational Safety and Health, Atlanta, Georgia, USA.ORCID 0000-0001-5935-1874
Mark P PurdueDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
James J BeaumontDepartment of Public Health Sciences, University of California Davis, Davis, California, USA.
Robert D DanielsWorld Trade Center Health Program, National Institute for Occupational Safety and Health, Washington, District of Columbia, USA.ORCID 0000-0002-3915-7991
National Institute for Occupational Safety and Health · USNational Cancer Institute · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFirefighters perform strenuous work in hot environments, which may increase their risk of chronic kidney disease. The purpose of this study was to evaluate the risk of end-stage renal disease (ESRD) and types of ESRD among a cohort of US firefighters compared to the US general population, and to examine exposure-response relationships.

methodsESRD from 1977 through 2014 was identified through linkage with Medicare data. ESRD incidence in the cohort compared to the US population was evaluated using life table analyses. Associations of all ESRD, systemic ESRD, hypertensive ESRD, and diabetic ESRD with exposure surrogates (exposed days, fire runs, and fire hours) were examined in Cox proportional hazards models adjusted for attained age (the time scale), race, birth date, fire department, and employment duration.

resultsThe incidence of all ESRD was less than expected (standardized incidence ratio (SIR) = 0.79; 95% confidence interval = 0.69-0.89, observed = 247). SIRs for ESRD types were not significantly increased. Positive associations of all ESRD, systemic ESRD, and hypertensive ESRD with exposed days were observed: however, 95% confidence intervals included one.

conclusionsWe found little evidence of increased risk of ESRD among this cohort of firefighters. Limitations included the inability to evaluate exposure-response relationships for some ESRD types due to small observed numbers, the limitations of the surrogates of exposure, and the lack of information on more sensitive outcome measures for potential kidney effects.

Indexed as

FirefightersKidney Failure, ChronicAgedChicagoHumansIncidenceMedicarePhiladelphiaSan FranciscoUnited Statesend-stage renal diseasefirefighterslongitudinal studies

Identifiers

PMID36268894
PMCPMC9828160
OpenAlexW4307036065

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.