Evidence map›Paper›PMID 36268877›Full record

ArticlePsychological medicine2023

Specifying the psychosocial pathways whereby child and adolescent adversity shape adult health outcomes.

Man-Kit Lei, Mark T Berg, Ronald L Simons, Steven R H Beach

Abstract read
In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Man-Kit LeiDepartment of Sociology, University of Georgia, Athens, GA, USA.ORCID 0000-0002-7757-6548
Mark T BergDepartment of Sociology and Criminology, University of Iowa, Iowa City, IA, USA.
Ronald L SimonsDepartment of Sociology, University of Georgia, Athens, GA, USA.
Steven R H BeachDepartment of Psychology, University of Georgia, Athens, GA, USA.

Funding

Contextual and Health Behavior Effects on Epigenetic Aging Among African AmericansR01CA220254 · NCI · UNIVERSITY OF CONNECTICUT STORRS · PI BEACH, STEVEN R, GIBBONS, FREDERICK X · 2018 to 2022
$3.5M
Psychosocial Context and the Biological Clock: Changes in Weathering during Middle-AgeR01AG055393 · NIA · UNIVERSITY OF GEORGIA · PI SIMONS, RONALD L · 2017 to 2021
$3.4M
Stress, Weathering, and Blood-Based Biomarkers of Alzheimer’s Disease: A Longitudinal Study of Low Income, Aging African AmericansRF1AG077386 · NIA · UNIVERSITY OF GEORGIA · PI MIELKE, MICHELLE M, SIMONS, RONALD L · 2022 to 2023
$3.2M
Biomarkers of Health Risk Among African American CouplesR01HD080749 · NICHD · UNIVERSITY OF GEORGIA · PI BEACH, STEVEN R, SIMONS, RONALD L · 2015 to 2019
$2.9M
Social Determinants of Inflammation and Metabolic Syndrom among African AmericansR01HL118045 · NHLBI · UNIVERSITY OF GEORGIA · PI SIMONS, RONALD L · 2014 to 2017
$2.3M
NCI NIH HHS R01 CA220254NHLBI NIH HHS R01 HL118045NIA NIH HHS R01 AG055393NIA NIH HHS RF1 AG077386NICHD NIH HHS R01 HD080749
6 · The paper itself

Abstract

backgroundSocial scientists generally agree that health disparities are produced, at least in part, by adverse social experiences, especially during childhood and adolescence. Building on this research, we use an innovative method to measure early adversity while drawing upon a biopsychosocial perspective on health to formulate a model that specifies indirect pathways whereby childhood and adolescent adversity become biologically embedded and influence adult health.

methodUsing nearly 20 years of longitudinal data from 382 Black Americans, we use repeated-measures latent class analysis (RMLCA) to construct measures of childhood/adolescent adversities and their trajectories. Then, we employ structural equation modeling to examine the direct and indirect effects of childhood/adolescent adversity on health outcomes in adulthood through psychosocial maladjustment.

resultsRMLCA identified two classes for each component of childhood/adolescent adversity across the ages of 10 to 18, suggesting that childhood/adolescent social adversities exhibit a prolonged heterogeneous developmental trajectory. The models controlled for early and adult mental health, sociodemographic and health-related covariates. Psychosocial maladjustment, measured by low self-esteem, depressive and anxiety symptoms, and lack of self-control, mediated the relationship between childhood/adolescent adversity, especially parental hostility, racial discrimination, and socioeconomic class, and both self-reported illness and blood-based accelerated biological aging (with proportion mediation ranging from 8.22% to 79.03%).

conclusionThe results support a biopsychosocial model of health and provide further evidence that, among Black Americans, early life social environmental experiences, especially parenting, financial stress, and racial discrimination, are associated with adult health profiles, and furthermore, psychosocial mechanisms mediate this association.

Indexed as

Child AbuseMental DisordersAdolescentAdultAnxietyChildHumansLife Change EventsOutcome Assessment, Health CareBiological agingminority populationprospective longitudinal designpsychosocial maladjustmentself-reported illnesssocial adversity

Identifiers

PMID36268877
PMCPMC10120399

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.