ArticleThe Journal of experimental biology2022
Metabolic rate increases with acclimation temperature and is associated with mitochondrial function in some tissues of threespine stickleback.
Article in The Journal of experimental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Mitochondrial respiratory capacities are not linked to individual variation in hypoxia tolerance and standard metabolic rate in European seabass Dicentrarchus labrax.Journal of fish biology · 2026Article
- Seasonal and spatial assessment of aquatic pollution in the Mediterranean crab Callinectes sapidus.Scientific reports · 2026Article
- Sirtuins may mediate temperature-induced metabolic remodeling in threespine stickleback.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025Article
- High Warming Restricts the Growth and Movement of a Larval Chinese Critically Endangered Relict Newt.Biology · 2025Article
- Putative neural and endocrine control of thermal acclimation in fish.Conservation physiology · 2025Article
- Non-lethal sampling for assessment of mitochondrial function does not affect metabolic rate and swimming performance.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Tissue-specific metabolic enzyme levels covary with whole-animal metabolic rates and life-history loci via epistatic effects.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- An evolving roadmap: using mitochondrial physiology to help guide conservation efforts.Conservation physiology · 2024Article
- Metabolic rate increases with acclimation temperature and is associated with mitochondrial function in some tissues of threespine stickleback.The Journal of experimental biology · 2022Article
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6 authors at 1 institution in 1 country.
Funding
Abstract
The metabolic rate (ṀO2) of eurythermal fishes changes in response to temperature, yet it is unclear how changes in mitochondrial function contribute to changes in ṀO2. We hypothesized that ṀO2 would increase with acclimation temperature in the threespine stickleback (Gasterosteus aculeatus) in parallel with metabolic remodeling at the cellular level but that changes in metabolism in some tissues, such as liver, would contribute more to changes in ṀO2 than others. Threespine stickleback were acclimated to 5, 12 and 20°C for 7 to 21 weeks. At each temperature, standard and maximum metabolic rate (SMR and MMR, respectively), and absolute aerobic scope (AAS) were quantified, along with mitochondrial respiration rates in liver, oxidative skeletal and cardiac muscles, and the maximal activity of citrate synthase (CS) and lactate dehydrogenase (LDH) in liver, and oxidative and glycolytic skeletal muscles. SMR, MMR and AAS increased with acclimation temperature, along with rates of mitochondrial phosphorylating respiration in all tissues. Low SMR and MMR at 5°C were associated with low or undetectable rates of mitochondrial complex II activity and a greater reliance on complex I activity in liver, oxidative skeletal muscle and heart. SMR was positively correlated with cytochrome c oxidase (CCO) activity in liver and oxidative muscle, but not mitochondrial proton leak, whereas MMR was positively correlated with CCO activity in liver. Overall, the results suggest that changes in ṀO2 in response to temperature are driven by changes in some aspects of mitochondrial function in some, but not all, tissues of threespine stickleback.
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