Evidence map›Paper›PMID 36268547›Full record

SynthesisInternational wound journal2023

The role of prophylactic antibiotics in elective inguinal tension-free hernia repair: A systematic review and meta-analysis.

Xiao-Jun Tian, Xian-Min Wang, Yue-Hua Lei, Deng-Chao Wang, Jian Wei, Zhao-Jun Fu, Yue-Juan Li

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiao-Jun TianDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, People's Republic of China.
Xian-Min WangDepartment of Pediatrics, Zigong Fourth People's Hospital, Zigong, Sichuan, People's Republic of China.
Yue-Hua LeiDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, People's Republic of China.ORCID https://orcid.org/0000-0002-9608-7723
Deng-Chao WangDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, People's Republic of China.
Jian WeiDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, People's Republic of China.
Zhao-Jun FuDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, People's Republic of China.
Yue-Juan LiDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whether to use antibiotics to prevent surgical site infection in elective inguinal tension-free hernia repair has been controversial. To systematically evaluate the effect of prophylactic antibiotic application in elective inguinal tension-free hernia repair, we identified all published randomised controlled trials of the effect of prophylactic antibiotic application on elective inguinal tension-free hernia repair were collected by computer retrieval from the China National Knowledge Infrastructure; VIP Database; Wanfang Database; China Biomedical Literature Database; and PubMed, EMBASE and Cochrane Library databases. Meta-analysis was performed by RevMan 5.3 software. The meta-analysis showed that the total incidence of surgical site infections [P = 0.003] and the incidence of superficial surgical site infections [P = 0.004] in the antibiotic group (AG) were lower than those in the non-antibiotic group (NAG). There was no significant difference in the total incidence of postoperative infections [P = 0.06], deep surgical site infections [P = 0.26] and seroma [P = 0.52] between the AG and the NAG. Based on current evidence, the application of prophylactic antibiotics in elective inguinal tension-free hernia repair can prevent the total incidence of surgical site infections and that of superficial surgical site infections but cannot prevent the total incidence of postoperative infection events, incidence of deep surgical site infections and incidence of seroma.

Indexed as

Hernia, InguinalSurgical Wound InfectionAnti-Bacterial AgentsAntibiotic ProphylaxisHerniorrhaphyHumansSeromaSurgical MeshAnti-Bacterial Agentshernia repairmeta-analysisprophylactic antibiotics

Identifiers

PMID36268547
PMCPMC10031234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.