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ArticleAnnals of medicine and surgery (2012)2022

Bilateral simultaneous primary Oral Squamous Cell Carcinoma: A rare presentation.

Maira Adeel, Hira Andaleeb, Saad Shakil, Sareema Eman Akhtar, Talal Almas, Abdulla K AlSubai, Sara AlNajdi, Aryam Mohammed Alenizi, Khaled Saeed Obaid Aldhaheri, Shakil Aqil

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Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Maira AdeelDepartment of Otorhinolaryngology - Head and Neck Surgery, Liaquat National Hospital and Medical College, Pakistan.
Hira AndaleebDepartment of Otorhinolaryngology - Head and Neck Surgery, Liaquat National Hospital and Medical College, Pakistan.
Saad ShakilZiauddin Medical College, Karachi, Pakistan.
Sareema Eman AkhtarZiauddin Medical College, Karachi, Pakistan.
Talal AlmasRCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, Dublin 2, Ireland.
Abdulla K AlSubaiRCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, Dublin 2, Ireland.
Sara AlNajdiRCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, Dublin 2, Ireland.
Aryam Mohammed AleniziRCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, Dublin 2, Ireland.
Khaled Saeed Obaid AldhaheriRCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, Dublin 2, Ireland.
Shakil AqilDepartment of Otorhinolaryngology - Head and Neck Surgery, Liaquat National Hospital and Medical College, Pakistan.
Royal College of Surgeons in Ireland · IELiaquat National Hospital · PKZiauddin University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: and Importance: Oral Squamous Cell Carcinoma (OSSC) is one of the most common malignancies of the oral cavity and is one of the ten most prevalent tumours in the world. Control of this tumor is difficult and challenging as its propensity to spread is embedded in the cancer field of epithelial cells which alter these cells and induce a malignant potential within them. Simultaneous bilateral primary tumours are a rare presentation in the oral cavity which highlights the significance of early diagnosis and treatment. Case presentation: Here we present a case of 50-year-old gentleman known case of diabetes, hypertension and chronic history of beetle nut chewing who developed a simultaneously growing bilateral primary OSSC in the buccal mucosa. CT scan revealed a heterogeneous enhancing thickening in the bilateral buccogingival mucosa. A wide local excision of bilateral buccal mucosa with bilateral marginal mandibulectomy with neck dissection was planned. Clinical discussion: The majority of the case report emphasises the relevance of simultaneously developing bilateral primary oral cavity tumours in a patient who had a history of consuming beetle nuts. The independent incidence of bilateral primary OSSC in individuals without a history of tobacco, beetle nut, or alcohol use has also been documented in a small body of research. Due to the considerable clinical variety in its presentation, it is necessary to include bilateral primary OSSC when making a differential diagnosis of OSSC. Conclusion: Multiple bilateral primary tumours of the oral cavity are typically on the rise. The prognosis and survival of these individuals are considerably improved by close surveillance and early, expectant management of these cancers. This case study emphasises the value of thorough screening techniques used at an early stage to find these lesions and treat them appropriately.

Indexed as

Bilateral buccal mucosa tumorBilateral primary tumorBilateral simultaneous primary OSCCOral carcinomaSimultaneous tumorSquamous cell carcinoma

Identifiers

PMID36268450
PMCPMC9577514
OpenAlexW4296122028

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.