Evidence map›Paper›PMID 36268411›Full record

ArticleAnnals of medicine and surgery (2012)2022

Successful use of therapeutic anticoagulation therapy in two patients with moderate stroke from the second day of onset: A case report and literature review.

Mostafa Meshref, Nour Shaheen, Rehab Adel Diab, Mariam Tarek Desouki, Yara Amro, Shiamaa M Khairat, Mohamed Ali, Mahmoud Galal Ahmed

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mostafa MeshrefNeurology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Nour ShaheenFaculty of Medicine, Alexandria University, Alexandria, Egypt.
Rehab Adel DiabFaculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mariam Tarek DesoukiNeurology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Yara AmroPharmacist Ministry of Health, Cairo, Egypt.
Shiamaa M KhairatDivision of Neurology Medicine, Department of Internal Medicine, King Khalid Hospital Hail, Saudi Arabia.
Mohamed AliNeurology Department, Louisiana State University, Shreveport, LA, USA.
Mahmoud Galal AhmedNeurology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and importance: Hemorrhagic transformation of ischemic stroke is one of the most traumatic consequences of ischemic stroke. Therefore, deciding the optimal time for anticoagulant application and its effect on clinical outcome, recurrence and risk for hemorrhagic transformation are still in quarry. The European Heart Rhythm Association recommends the usage of anticoagulants after 3-4 days after a mild stroke, 6 days after moderate stroke and 12 days after a severe stroke. Case presentation: In our case report, we present two patients who started full therapeutic anticoagulation of low molecular weight heparin from the first day after moderate ischemic stroke, warfarin was added later guided by INR and discharged on oral anticoagulants for associated AF. They improved clinically with improved motor function for both upper and lower limbs, sensation and gaze without any complication followed by serial CT. Clinical discussion and conclusion: As a result of this case report, clinical improvement has not been associated with hemorrhagic sequelae of anticoagulant administration on the first day. At this point, we recommend conducting a trial to study the effect of early application of anticoagulants from the first day on clinical outcome, recurrence, and hemorrhagic transfusion of stroke.

Indexed as

AnticoagulantsAtrial fibrillationIschemic strokeStrokeWarfarin

Identifiers

PMID36268411
PMCPMC9577847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.