Evidence map›Paper›PMID 36268223›Full record

ArticleFrontiers in cellular and infection microbiology2022

Analysis of the blood bacterial composition of patients with acute coronary syndrome and chronic coronary syndrome.

Ikram Khan, Imran Khan, Muhammad Usman, Zhou Jianye, Zhang Xiao Wei, Xie Ping, Li Zhiqiang, An Lizhe

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Observational
  5. Pathological Alterations in Human Blood Microbiome-An Updated Review.International journal of molecular sciences · 2025
    Review
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ikram KhanDepartment of Microbiology, School of Life Sciences, Lanzhou University, Lanzhou, China.
Imran KhanDepartment of Microbiology, Khyber Medical University Peshawar, Peshawar, Pakistan.
Muhammad UsmanState Key Laboratory of Grassland Agro-ecosystem, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Ruler Affairs, College of Pastoral Agriculture Sciences and Technology, Lanzhou University, Lanzhou, China.
Zhou JianyeSchool of Stomatology, Northwest Minzu University, Lanzhou, China.
Zhang Xiao WeiDepartment of Cardiology, Lanzhou University Second Hospital, Lanzhou, China.
Xie PingDepartment of Cardiology, Gansu Provincial Hospital, Lanzhou, China.
Li ZhiqiangSchool of Stomatology, Northwest Minzu University, Lanzhou, China.
An LizheDepartment of Microbiology, School of Life Sciences, Lanzhou University, Lanzhou, China.
Lanzhou University · CNMinzu University of China · CNGansu Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence revealed that the blood microbiota plays a role in several non-communicable diseases, including cardiovascular disease. However, the role of circulating microbes in atherosclerosis remains understudied. To test this hypothesis, we performed this study to investigate the microbial profile in the blood of Chines atherosclerosis volunteers. A total of seventy Acute Coronary Syndrome patients, seventy Chronic Coronary Syndrome patients, and seventy healthy individuals were examined using high-throughput Illumina Novaseq targeting the V3-V4 regions of the 16S rRNA gene. The relationship between atherosclerosis and blood microbiome, clinical variables, and their functional pathways were also investigated. Our study observed significantly higher alpha diversity indices (Chao1,

Indexed as

Acute Coronary SyndromeAtherosclerosisBacteriaBiomarkersHumansRNA, Ribosomal, 16SBiomarkersRNA, Ribosomal, 16Sacute coronary syndromebacteriablood microbiotachronic coronary syndromenovaSeq

Identifiers

PMID36268223
PMCPMC9577097
OpenAlexW4300818892

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.