Evidence map›Paper›PMID 36268209›Full record

ReviewFrontiers in surgery2022

A systematic review and meta-analysis on delaying surgery for urothelial carcinoma of bladder and upper tract urothelial carcinoma: Implications for the COVID19 pandemic and beyond.

Jeffrey J Leow, Wei Shen Tan, Wei Phin Tan, Teck Wei Tan, Vinson Wai-Shun Chan, Kari A O Tikkinen, Ashish Kamat, Shomik Sengupta, Maxwell V Meng, Shahrokh Shariat and 9 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 16 institutions in 14 countries.

Jeffrey J LeowDepartment of Urology, Tan Tock Seng Hospital, Singapore, Singapore.
Wei Shen TanDivision of Surgery and Interventional Science, University College London, London, United Kingdom.
Wei Phin TanDepartment of Urology, NYU Langone Health, New York City, NY, United States.
Teck Wei TanDepartment of Urology, Tan Tock Seng Hospital, Singapore, Singapore.
Vinson Wai-Shun ChanRoyal Derby Hospital, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, United Kingdom.
Kari A O TikkinenDepartment of Urology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Ashish KamatDepartment of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Shomik SenguptaUrology Department, Eastern Health, Box Hill, Victoria, Australia.
Maxwell V MengDepartment of Urology, University of California San Francisco, San Francisco, CA, United States.
Shahrokh ShariatDepartment of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Morgan RoupretSorbonne University, GRC N 5, Predicitive Onco-uro, AP-HP, Hôpital Pitié-Salpêtriére, Paris, France.
Karel DecaesteckerDepartment of Urology, AZ Maria Middelares Hospital, Ghent, Belgium.
Nikhil VasdevDepartment of Urology, Hertfordshire and Bedfordshire Urological Cancer Centre, Lister Hospital Stevenage, School of Medicine and Life Sciences, University of Hertfordshire, Hatfield, United Kingdom.
Yew Lam ChongDepartment of Urology, Tan Tock Seng Hospital, Singapore, Singapore.
Dmitry EnikeevDepartment of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Gianluca GiannariniUrology Unit, Santa Maria della Misericordia University Hospital, Udine, Italy.
Vincenzo FicarraDepartment of Human and Pediatric Pathology "Gaetano Barresi", Urologic Section, University of Messina, Messina, Italy.
Jeremy Yuen-Chun TeohS.H. Ho Urology Centre, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
UroSoMe Collaborators
Nanyang Technological University · SGUniversity College London · GBComprehensive Cancer Center Vienna · ATCornell University · USEastern Health · AUGhent University · BELister Hospital · GBOspedale Santa Maria della Misericordia di Udine · ITPrince of Wales Hospital · CNSorbonne Université · FRSouth Karelia Central Hospital · FITan Tock Seng Hospital · SGThe University of Texas MD Anderson Cancer Center · USUniversity College Hospital · GBUniversity of California, San Francisco · USUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The COVID-19 pandemic has led to competing strains on hospital resources and healthcare personnel. Patients with newly diagnosed invasive urothelial carcinomas of bladder (UCB) upper tract (UTUC) may experience delays to definitive radical cystectomy (RC) or radical nephro-ureterectomy (RNU) respectively. We evaluate the impact of delaying definitive surgery on survival outcomes for invasive UCB and UTUC. Methods: We searched for all studies investigating delayed urologic cancer surgery in Medline and Embase up to June 2020. A systematic review and meta-analysis was performed. Results: We identified a total of 30 studies with 32,591 patients. Across 13 studies ( Conclusions: A delay from diagnosis of UCB or UTUC to definitive RC or RNU was associated with poorer survival outcomes. This was not the case for patients who received neoadjuvant chemotherapy.

Indexed as

bladder cancerbladder carcinomadelayed treatmentdelay in surgerytime-to-treatmentureteral neoplasmsurinary bladder neoplasmsurothelial carcinoma

Identifiers

PMID36268209
PMCPMC9577485
OpenAlexW4301396694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.