Evidence map›Paper›PMID 36267858›Full record

ArticleJournal of pediatric genetics2022

Acute COVID-19 Infection in a Pediatric Patient with ROHHAD.

Daniel S Udrea, Merrick Lopez, Michael Avesar, Sonea Qureshi, Anthony Moretti, Shamel A Abd-Allah, Harsha K Chandnani

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of pediatric genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Daniel S UdreaDepartment of Emergency Medicine, Loma Linda University Medical Center, Loma Linda, California, United States.ORCID 0000-0003-4502-1078
Merrick LopezDivision of Pediatric Critical Care, Department of Pediatrics, Loma Linda University Children's Hospital, Loma Linda, California, United States.
Michael AvesarDivision of Pediatric Critical Care, Department of Pediatrics, Loma Linda University Children's Hospital, Loma Linda, California, United States.
Sonea QureshiDivision of Pediatric Critical Care, Department of Pediatrics, Loma Linda University Children's Hospital, Loma Linda, California, United States.
Anthony MorettiDivision of Pediatric Critical Care, Department of Pediatrics, Loma Linda University Children's Hospital, Loma Linda, California, United States.
Shamel A Abd-AllahDivision of Pediatric Critical Care, Department of Pediatrics, Loma Linda University Children's Hospital, Loma Linda, California, United States.
Harsha K ChandnaniDivision of Pediatric Critical Care, Department of Pediatrics, Loma Linda University Children's Hospital, Loma Linda, California, United States.
Loma Linda University Children's Hospital · USLoma Linda University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel coronavirus (severe acute respiratory syndrome coronavirus-2) has led to a global pandemic. In the adult population, coronavirus disease 2019 (COVID-19) has been found to cause multiorgan system damage with predicted long-term sequelae. We present a case of a 10-year-old boy with a history of ROHHAD (rapid-onset obesity with hypothalamic dysregulation, hypoventilation, and autonomic dysregulation) who presented with hypoxia, emesis, and abdominal pain. Imaging found bilateral ground glass opacities in the lungs and a pericardial effusion. Laboratory evaluation was concerning for elevated inflammatory markers. Remdesivir, hydroxychloroquine, and anticoagulation (heparin and enoxaparin) were utilized. The patient's severe respiratory failure was managed with conventional mechanical ventilation, inhaled nitric oxide, and airway pressure release ventilation. We hope that this report provides insight into the course and management of the severe acute pediatric COVID-19 patient, specifically with underlying comorbidities such as ROHHAD. Clinical trial registration is none.

Indexed as

COVID-19inflammatory syndromeROHHAD

Identifiers

PMID36267858
PMCPMC9578773
OpenAlexW3095991167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.