Evidence map›Paper›PMID 36267838›Full record

ArticleBioMed research international2022

Cytotoxicity of Hybrid Noble Metal-Polymer Composites.

Anton Tkachenko, Pavlo Virych, Valeriy Myasoyedov, Volodymyr Prokopiuk, Anatolii Onishchenko, Dmytro Butov, Yuliia Kuziv, Oleg Yeshchenko, Sican Zhong, Guochao Nie and 1 more

Abstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Apoptosis and eryptosis: similarities and differences.Apoptosis : an international journal on programmed cell death · 2024
    Review
  6. Antibacterial and antioxidant activity of gold and silver nanoparticles in dextran-polyacrylamide copolymers.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anton TkachenkoResearch Institute of Experimental and Clinical Medicine, Kharkiv National Medical University, Kharkiv 61022, Ukraine.ORCID https://orcid.org/0000-0002-1029-1636
Pavlo VirychFaculty of Chemistry, Taras Shevchenko National University of Kyiv, Kyiv 01033, Ukraine.ORCID https://orcid.org/0000-0002-1463-1992
Valeriy MyasoyedovDepartment of Medical Biology, Kharkiv National Medical University, Kharkiv 61022, Ukraine.ORCID https://orcid.org/0000-0001-7135-4672
Volodymyr ProkopiukResearch Institute of Experimental and Clinical Medicine, Kharkiv National Medical University, Kharkiv 61022, Ukraine.ORCID https://orcid.org/0000-0003-4379-4130
Anatolii OnishchenkoResearch Institute of Experimental and Clinical Medicine, Kharkiv National Medical University, Kharkiv 61022, Ukraine.ORCID https://orcid.org/0000-0002-2122-2361
Dmytro ButovDepartment of Phthisiology and Pulmonology, Kharkiv National Medical University, Kharkiv 61022, Ukraine.
Yuliia KuzivFaculty of Chemistry, Taras Shevchenko National University of Kyiv, Kyiv 01033, Ukraine.ORCID https://orcid.org/0000-0001-8005-8197
Oleg YeshchenkoFaculty of Physic, Taras Shevchenko National University of Kyiv, Kyiv 01033, Ukraine.ORCID https://orcid.org/0000-0001-8927-5673
Sican ZhongGuangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology, Yulin Normal University, Yulin 537000, China.ORCID https://orcid.org/0000-0003-1511-8872
Guochao NieGuangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology, Yulin Normal University, Yulin 537000, China.ORCID https://orcid.org/0000-0001-8563-0607
Nataliya KutsevolFaculty of Chemistry, Taras Shevchenko National University of Kyiv, Kyiv 01033, Ukraine.ORCID https://orcid.org/0000-0002-1468-4111

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present research was to assess the cytotoxicity of gold and silver nanoparticles synthesized into dextran-graft-polyacrylamide (D-PAA) polymer nanocarrier, which were used as a basis for further preparation of multicomponent nanocomposites revealed high efficacy for antitumor therapy. The evaluation of the influence of Me-polymer systems on the viability and metabolic activity of fibroblasts and eryptosis elucidating the mechanisms of the proeryptotic effects has been done in the current research. The nanocomposites investigated in this study did not reduce the survival of fibroblasts even at the highest used concentration. Our findings suggest that hybrid Ag/D-PAA composite activated eryptosis via ROS- and Ca

Indexed as

Metal NanoparticlesNanocompositesDextransGoldPolymersReactive Oxygen SpeciesSilverDextransGoldPolymersReactive Oxygen SpeciesSilver

Identifiers

PMID36267838
PMCPMC9578826

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.