ReviewFrontiers in medicine2022
Therapeutic strategies for oral lichen planus: State of the art and new insights.
Review in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- A systematic review of the role of interleukin inhibitors in lichen planus: therapeutic and paradoxical effects.Inflammopharmacology · 2025Pooled it
- Efficacy and safety of topical clobetasol propionate in comparison with alternative treatments in oral lichen planus: an updated systematic review and meta-analysis.Frontiers in medicine · 2024Pooled it
- Efficacy of Platelet-Rich Plasma Therapy in Oral Lichen Planus: A Systematic Review.Medicina (Kaunas, Lithuania) · 2023Pooled it
- The role of vitamin D in amelioration of oral lichen planus and its effect on salivary and tissue IFN-γ level: a randomized clinical trial.BMC oral health · 2024Trial
- Autoimmune Oral Mucosal Diseases in Older Patients: An Overview of Early Recognition and Management in the Primary Care Setting.Geriatrics (Basel, Switzerland) · 2026Review
- Unlocking Potential ofGels (Basel, Switzerland) · 2026Article
- Analysis of the efficacy of photobiomodulation therapy in the treatment of oral lichen planus: A systematic review and meta-analysis of randomized and non-randomized clinical trials.Journal of clinical and experimental dentistry · 2026Review
- Clinicopathological characteristics and follow-up outcomes of patients with oral potentially malignant disorders: A 7-year observational cohort study.Scientific reports · 2026Observational
- The Relative Frequency of Oral Lichen Planus and Oral Lichenoid Lesions in a New Zealand Population Diagnosed at a Specialist Reference Centre.Clinical and experimental dental research · 2026Article
- The Subepithelial Bandlike Distribution Pattern of the CD4 Biomarker May Determine Oral Lichen Planus in the Absence of Typical Microscopic Features.International journal of molecular sciences · 2026Article
- Measuring pain in oral lichen planus: a comparative study of four assessment scales and their correlation.Scientific reports · 2026Observational
- Refractory oral and cutaneous lichen planus successfully treated with upadacitinib.JAAD case reports · 2026Article
- Molecular and Cellular Basis of Oral Lichen Planus: Bridging Pathogenesis and Modern Clinical Paradigms.International journal of molecular sciences · 2026Review
- IFN-I Induces Keratinocytes Necroptosis via ZBP1-MLKL Axis in Oral Lichen Planus.Inflammation · 2026Article
- Identification and Mechanism Research of Oxidative Stress-Related Biomarkers in Oral Lichen Planus.Biomedicines · 2026Article
- Article
- Vitamin C in Oral Lichen Planus: Pathobiological Rationale and Therapeutic Potential.International journal of molecular sciences · 2025Review
- Article
- Overexpression of miR-516a-5p Promotes Erosive Oral Lichen Planus: In Vitro Study Based on Bioinformatics Analyses.Clinical and experimental dental research · 2025Article
- Immunomodulatory Effects of a High-CBD Cannabis Extract: A Comparative Analysis with Conventional Therapies for Oral Lichen Planus and Graft-Versus-Host Disease.International journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa. Several clinical subtypes of OLP have been reported, including the reticular and erosive one. On the one hand, reticular OLP is usually asymptomatic and is characterized by white streaks surrounded by well-defined erythematous borders. On the other hand, erosive OLP shows ulcerations and erosions surrounded by erythematous mucosa. While reticular OLP is relatively easy to control, erosive OLP is extremely painful and refractory to therapies, limiting the quality of life of the patients. In addition, treating erosive OLP is extremely tricky, and a gold standard treatment has not yet been established. However, several therapeutic approaches have been reported as effective, including systemic corticosteroids, systemic retinoids, and anti-interleukin (IL)-17/anti-IL-23 drugs. Indeed, our group and other several authors reported the effectiveness of anti-IL17, anti-IL12/23, and anti-IL23 agents in refractory OLP, highlighting the urgency of clinical studies on the use of anti-IL agents in OLP patients. In this paper, we reviewed the English- and German-language literature about therapeutic strategies for treating OLP, focusing on new systemic therapies for erosive OLP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.