Evidence map›Paper›PMID 36267460›Full record

SynthesisDisease markers2022

Neutrophil to Lymphocyte Ratio as a Biomarker for Predicting the Coronary Artery Abnormality in Kawasaki Disease: A Meta-Analysis.

Shirin Sarejloo, Matin Moallem Shahri, Pouria Azami, Alec Clark, Ethan Hass, Maryam Salimi, Brandon Lucke-Wold, Shahram Sadeghvand, Shokoufeh Khanzadeh

Open access · hybridAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  4. METTL3-mediated mApplied biochemistry and biotechnology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Shirin SarejlooCardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Matin Moallem ShahriDepartment of Thoracic Surgery, Thoracic Surgery Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Pouria AzamiCardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Alec ClarkUniversity of Central Florida College of Medicine, USA.
Ethan HassUniversity of Central Florida College of Medicine, USA.
Maryam SalimiBone and Joint Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID https://orcid.org/0000-0001-9771-7048
Brandon Lucke-WoldDepartment of Neurosurgery, University of Florida, Gainesville, Florida, USA.
Shahram SadeghvandPediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Shokoufeh KhanzadehStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-4177-8746
Shiraz University of Medical Sciences · IRTabriz University of Medical Sciences · IRUniversity of Central Florida · USMashhad University of Medical Sciences · IRUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a systematic review and meta-analysis on the relationship between the neutrophil to lymphocyte ratio (NLR) and coronary artery abnormalities (CAA) in patients with Kawasaki disease (KD), according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements. We searched PubMed, Scopus, Web of Science, Embase, TRIP, Google Scholar, and ProQuest up to the 8th of August 2022. This was done to retrieve eligible studies. No date or language limitations were considered in this study. Methodology quality assessment was conducted according to the Newcastle-Ottawa scale (NOS). Standard mean difference (SMD) and its 95% confidence interval (CI) were used to depict the pooled continuous variables. Finally, 17 articles with 6334 KD patients, of whom 1328 developed CAA, were enrolled in this meta-analysis. NLR level was significantly higher in KD patients with CAA compared to those without CAA (SMD =0.81; 95% CI =0.05-1.57,

Indexed as

AneurysmCoronary Artery DiseaseMucocutaneous Lymph Node SyndromeBiomarkersHumansLymphocytesNeutrophilsBiomarkers

Identifiers

PMID36267460
PMCPMC9578863
OpenAlexW4304607615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.